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RGS3 gene

Known as: REGULATOR OF G PROTEIN SIGNALING 3, C2PA, regulator of G-protein signaling 3 
This gene plays a role in the negative regulation of signal transduction.
National Institutes of Health

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3 relations
RGS3 protein, humanSignal Transduction

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RGS3 wt Allele

Papers overview

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Highly Cited
2006
Highly Cited
2006
Regulation of cardiomyocyte signaling by RGS proteins: differential selectivity towards G proteins and susceptibility to regulation.
Highly Cited
2004
Highly Cited
2004
Toll-Like Receptor Signaling Alters the Expression of Regulator of G Protein Signaling Proteins in Dendritic Cells: Implications for G Protein-Coupled Receptor Signaling
Conserved structural motifs on pathogens trigger pattern recognition receptors present on APCs such as dendritic cells (DCs). An… 
Highly Cited
2004
Highly Cited
2004
Differential Contribution of GTPase Activation and Effector Antagonism to the Inhibitory Effect of RGS Proteins on Gq-mediated Signaling in Vivo*
RGS proteins act as negative regulators of G protein signaling by serving as GTPase-activating proteins (GAP) for α subunits of… 
Highly Cited
2002
Highly Cited
2002
Receptor-selective Effects of Endogenous RGS3 and RGS5 to Regulate Mitogen-activated Protein Kinase Activation in Rat Vascular Smooth Muscle Cells*
Regulators of G protein signaling (RGS) proteins compose a highly diverse protein family best known for inhibition of G protein… 
Highly Cited
2001
Highly Cited
2001
Expression of RGS3, RGS4 and Gi alpha 2 in acutely failing donor hearts and end-stage heart failure.
BACKGROUND Regulators of G-protein Signalling (RGS) proteins have been shown to limit in vitro signalling of G proteins. In… 
Highly Cited
2000
Highly Cited
2000
Specific regulation of RGS2 messenger RNA by angiotensin II in cultured vascular smooth muscle cells.
The effects of angiotensin II (Ang II) are mediated primarily by Ang II type 1 receptors, which in turn are coupled to… 
Highly Cited
1999
Highly Cited
1999
RGS3 Inhibits G Protein-Mediated Signaling via Translocation to the Membrane and Binding to Gα11
ABSTRACT In the present study, we investigated the function and the mechanism of action of RGS3, a member of a family of proteins… 
Highly Cited
1997
Highly Cited
1997
RGS proteins reconstitute the rapid gating kinetics of Gβγ-activated inwardly rectifying K+ channels
G protein gated inward rectifier K+ (GIRK) channels mediate hyperpolarizing postsynaptic potentials in the nervous system and in… 
Highly Cited
1997
Highly Cited
1997
A Truncated Form of RGS3 Negatively Regulates G Protein-coupled Receptor Stimulation of Adenylyl Cyclase and Phosphoinositide Phospholipase C*
Identification of a new family of proteins (RGS proteins) that function as negative regulators ofG protein signaling has sparked… 
Highly Cited
1997
Highly Cited
1997
Potential role for a regulator of G protein signaling (RGS3) in gonadotropin-releasing hormone (GnRH) stimulated desensitization.
The cellular and molecular mechanisms of gonadotrope desensitization are unknown but transduction of the GnRH signal is known to… 
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