Ischemia induces regulator of G protein signaling 2 (RGS2) protein upregulation and enhances apoptosis in astrocytes.
- M. Endale, Sung Dae Kim, +8 authors M. Rhee
- Biology, Medicine
- American journal of physiology. Cell physiology
- 1 March 2010
Regulator of G protein signaling (RGS) family members, such as RGS2, interact with Galpha subunits of heterotrimeric G proteins, accelerating the rate of GTP hydrolysis and attenuating the… Expand
Prevalence of Benign Prostatic Hyperplasia on Jeju Island: Analysis from a Cross-sectional Community-based Survey
Purpose We report on the prevalence of benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS) among men of Jeju Island, representing a coastal and insular area, using a… Expand
Protective effect of genistein on radiation-induced intestinal injury in tumor bearing mice
- T. G. Son, Eun Ji Gong, +5 authors J. S. Kim
- BMC Complementary and Alternative Medicine
- 14 May 2013
BackgroundRadiation therapy is the most widely used treatment for cancer, but it causes the side effect of mucositis due to intestinal damage. We examined the protective effect of genistein in… Expand
Changes in bacterial species and antibiotic sensitivity in intensive care unit: acquired urinary tract infection during 10 years interval (2001-2011).
PURPOSE Patients in the intensive care unit (ICU) are usually at greater risk for acquiring urinary tract infections (UTIs). Few studies have focused on UTIs specifically acquired within the ICU. We… Expand
Baicalein inhibits agonist- and tumor cell-induced platelet aggregation while suppressing pulmonary tumor metastasis via cAMP-mediated VASP phosphorylation along with impaired MAPKs and PI3K-Akt…
Recently, the importance of platelet activation in cancer metastasis has become generally accepted. As a result, the development of new platelet inhibitors with minimal adverse effects is now a… Expand
Bub1 is required for maintaining cancer stem cells in breast cancer cell lines
Breast cancer is a leading cause of death among women worldwide due to therapeutic resistance and cancer recurrence. Cancer stem cells are believed to be responsible for resistance and recurrence.… Expand
Xenogeneic interaction between human CD40L and porcine CD40 activates porcine endothelial cells through NF-kappaB signaling.
Xenotransplantation is a promising alternative to overcome donor shortage in transplantation. CD40 molecule plays an important role in the interaction of T cells with antigen-presenting cells and in… Expand
A possible usage of a CDK4 inhibitor for breast cancer stem cell-targeted therapy.
Cancer stem cells (CSCs) are one of the main reasons behind cancer recurrence due to their resistance to conventional anti-cancer therapies. Thus, many efforts are being devoted to developing… Expand
The expression patterns of RGS transcripts in platelets
Regulators of G protein signalling (RGS) are involved in the negative regulation of cell activation processes and are involved in the pathophysiology of cardiovascular diseases. To get some further… Expand
Evaluation of antioxidant, antinociceptive, and anti‐inflammatory activities of ethanol extracts from Aloe saponaria Haw.
- E. A. Yoo, Sung Dae Kim, +5 authors M. Rhee
- Chemistry, Medicine
- Phytotherapy research : PTR
- 1 October 2008
Aloe species are traditionally prescribed for hypertension, burning, and rheumatoid arthritis. To elucidate the mechanism of the antihypertensive and anti‐inflammatory activities of this herb, the… Expand