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RARB protein, human

Known as: Retinoic Acid Receptor Beta 2, Nuclear Receptor Subfamily 1 Group B Member 2, RAR-Epsilon 
Retinoic acid receptor beta (455 aa, ~50 kDa) is encoded by the human RARB gene. This protein plays a role in the modulation of retinoic acid… 
National Institutes of Health

Related topics

Related topics

28 relations
Biologic DevelopmentCell Differentiation processCell NucleusCell Proliferation

Broader (1)

retinoic acid receptor beta

Papers overview

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Highly Cited
2010
Highly Cited
2010
Molecular Analysis of Plasma DNA for the Early Detection of Lung Cancer by Quantitative Methylation-Specific PCR
Purpose: Aberrant promoter hypermethylation of tumor suppressor genes is a promising marker for lung cancer detection. We… 
Review
2009
Review
2009
Developmental expression of retinoic acid receptors (RARs)
Here, I review the developmental expression features of genes encoding the retinoic acid receptors (RARs) and the ‘retinoid X’ or… 
Highly Cited
2007
Highly Cited
2007
Apo-10'-lycopenoic acid inhibits lung cancer cell growth in vitro, and suppresses lung tumorigenesis in the A/J mouse model in vivo.
High intake of lycopene has been associated with a lower risk of a variety of cancers including lung cancer. We recently showed… 
Highly Cited
2005
Highly Cited
2005
Reversal of Hypermethylation and Reactivation of p16INK4a, RARβ, and MGMT Genes by Genistein and Other Isoflavones from Soy
Purpose: We have previously shown the reactivation of some methylation-silenced genes in cancer cells by (−)-epigallocatechin-3… 
Highly Cited
2005
Highly Cited
2005
Down-Regulation of Retinoic Acid Receptor 3 in Mammary Carcinoma Cell Lines and Its Up-Regulation in Senescing Normal Mammary Epithelial Cells 1
Retinoids are important cellular, dietary factors that regulate differentiation and cellular growth. They serve as ligands for… 
Highly Cited
2003
Highly Cited
2003
CpG island methylation in carcinoid and pancreatic endocrine tumors
Carcinoid tumors and pancreatic endocrine tumors (PETs) are uncommon neuroendocrine neoplasms and their genetic alterations are… 
Highly Cited
2000
Highly Cited
2000
Evidence That Retinoic Acid Receptor β Induction by Retinoids Is Important for Tumor Cell Growth Inhibition*
Retinoic acid receptor β (RARβ) is thought to be involved in suppressing cell growth and tumorigenicity. Many premalignant and… 
Highly Cited
1999
Highly Cited
1999
Identification of a Novel Class of Retinoic Acid Receptor β-Selective Retinoid Antagonists and Their Inhibitory Effects on AP-1 Activity and Retinoic Acid-induced Apoptosis in Human Breast Cancer…
Four candidate retinoid antagonists (LE135, LE511, LE540, and LE550) were designed on the basis of the ligand superfamily concept… 
Highly Cited
1995
Highly Cited
1995
Expression of retinoic acid receptor beta mediates retinoic acid-induced growth arrest and apoptosis in breast cancer cells.
The expression of the retinoic acid receptor beta (RAR beta) mRNA is absent or down-regulated in most human breast cancer cell… 
Highly Cited
1991
Highly Cited
1991
High frequency of retinoic acid receptor beta abnormalities in human lung cancer.
One of the three human retinoic acid receptors, RAR-beta, maps to a region on the short arm of chromosome 3 frequently deleted in… 
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