Skip to search formSkip to main contentSkip to account menu

RALBP1 gene

Known as: RLIP76, RALBP1, RALA-BINDING PROTEIN 1 
This gene is involved in the regulation of small GTPase activity.
National Institutes of Health

Related topics

Related topics

3 relations
ChemotaxisS-(dinitrophenyl)glutathione ATPaseSignal Transduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
RLIP76 Regulates PI3K/Akt Signaling and Chemo-Radiotherapy Resistance in Pancreatic Cancer
Purpose Pancreatic cancer is an aggressive malignancy with characteristic metastatic course of disease and resistance to… 
Highly Cited
2009
Highly Cited
2009
Regulated RalBP1 Binding to RalA and PSD-95 Controls AMPA Receptor Endocytosis and LTD
A two step mechanism was identified that regulates receptor endocytosis during the development of long-term depression (LTD), a… 
2008
2008
RLIP76 in defense of radiation poisoning.
Review
2007
Review
2007
The non-ABC drug transporter RLIP76 (RALBP-1) plays a major role in the mechanisms of drug resistance.
RLIP76 or Ral binding protein (RalBP-1) was initially cloned as a Ral-effector that was proposed as a link between Ral and Ras… 
Highly Cited
2006
Highly Cited
2006
RLIP76 (RalBP1) is an R-Ras effector that mediates adhesion-dependent Rac activation and cell migration
The Ras family of small GTPases regulates cell proliferation, spreading, migration and apoptosis, and malignant transformation by… 
Highly Cited
2005
Highly Cited
2005
RLIP76, a non-ABC transporter, and drug resistance in epilepsy
BackgroundPermeability of the blood-brain barrier is one of the factors determining the bioavailability of therapeutic drugs and… 
Review
2003
Review
2003
Transport of glutathione conjugates and chemotherapeutic drugs by RLIP76 (RALBP1): A novel link between G‐protein and tyrosine kinase signaling and drug resistance
Our studies have shown that RLIP76 (RALBP1), a 76 kDa Ral‐binding, Rho/Rac‐GAP and Ral effector protein, is a novel multispecific… 
2003
2003
Role of RLIP76 in lung cancer doxorubicin resistance: I. The ATPase activity of RLIP76 correlates with doxorubicin and 4-hydroxynonenal resistance in lung cancer cells.
RLIP76 functions as an ATP-dependent transporter of amphiphilic chemotherapeutic drugs such as doxorubicin (DOX, adriamycin), as… 
Highly Cited
2001
Highly Cited
2001
Functional reassembly of ATP-dependent xenobiotic transport by the N- and C-terminal domains of RLIP76 and identification of ATP binding sequences.
We have recently shown that RLIP76, a Ral-binding, GTPase-activating protein, is an ATP-dependent transporter of doxorubicin (DOX… 
Highly Cited
2000
Highly Cited
2000
RLIP76, an effector of the GTPase Ral, interacts with the AP2 complex: involvement of the Ral pathway in receptor endocytosis.
RLIP76 is a modular protein that was identified as a putative effector of Ral, a GTPase activated during Ras signaling. To… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)