RAD50 gene

Known as: hRad50, RAD50, S. CEREVISIAE, HOMOLOG OF, RAD50 
This gene plays a role in DNA double-strand break repair.

Topic mentions per year

Topic mentions per year

1976-2018
0204019762018

Papers overview

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Highly Cited
2010
Highly Cited
2010
BACKGROUND Asthma is a heterogeneous disease that is caused by the interaction of genetic susceptibility with environmental… (More)
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Highly Cited
2007
Highly Cited
2007
Inherited breast cancer is associated with germline mutations in ten different genes in pathways critical to genomic integrity… (More)
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Highly Cited
2003
Highly Cited
2003
MRE11, RAD50 and NBS1 form a highly conserved protein complex (the MRE11 complex) that is involved in the detection, signalling… (More)
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Highly Cited
2001
Highly Cited
2001
Saccharomyces cerevisiae RAD50 and MRE11 genes are required for the nucleolytic processing of DNA double-strand breaks. We have… (More)
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Highly Cited
2001
Highly Cited
2001
S. cerevisiae RAD50, MRE11, and XRS2 genes are required for telomere maintenance, cell cycle checkpoint signaling, meiotic… (More)
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Highly Cited
2000
Highly Cited
2000
Telomeres allow cells to distinguish natural chromosome ends from damaged DNA and protect the ends from degradation and fusion… (More)
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Highly Cited
1999
Highly Cited
1999
Telomere length is maintained by the de novo addition of telomere repeats by telomerase, yet recombination can elongate telomeres… (More)
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Highly Cited
1998
Highly Cited
1998
Genetic studies in yeast have indicated a role of the RAD50 and MRE11 genes in homologous recombination, telomere length… (More)
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Highly Cited
1998
Highly Cited
1998
MRE11 and RAD50 are known to be required for nonhomologous joining of DNA ends in vivo. We have investigated the enzymatic… (More)
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Highly Cited
1990
Highly Cited
1990
The RAD50 gene of S. cerevisiae is required during meiosis for both recombination and chromosome synapsis and is also required… (More)
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