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R 56865

Known as: R-56865, R56865 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (3)

BenzothiazolesCalcium Channel BlockersPiperidines

Papers overview

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Highly Cited
2000
Highly Cited
2000
Oxygen‐sensing persistent sodium channels in rat hippocampus
1 Persistent sodium channel activity was recorded before and during hypoxia from cell‐attached and inside‐out patches obtained… 
Highly Cited
1999
Highly Cited
1999
Effect of Na+/Ca2+ exchange inhibitor, KB‐R7943 on ouabain‐induced arrhythmias in guinea‐pigs
We investigated protective effects of KB‐R7943, a Na+/Ca2+ exchange (NCX) inhibitor, on ouabain‐induced tonotropy and arrhythmias… 
Review
1999
Review
1999
Drugs preventing Na+ and Ca2+ overload.
Cardiac intracellular Na+and Ca2+homeostasis is regulated by the concerted action of ion channels, pumps and exchangers. The Na… 
Highly Cited
1999
Highly Cited
1999
Ischemia/reperfusion-induced arrhythmias in anaesthetized rats: a role of Na+ and Ca2+ influx.
Highly Cited
1996
Highly Cited
1996
Effects of the Na+/H+-exchange inhibitor Hoe 642 on intracellular pH, calcium and sodium in isolated rat ventricular myocytes
Abstract The inhibitors of the Na+/H+-exchange (NHE1) system Hoe 694 and Hoe 642 possess cardioprotective effects in ischaemia… 
Highly Cited
1995
Highly Cited
1995
Ion Channel Involvement in Anoxic Depolarization Induced by Cardiac Arrest in Rat Brain
Anoxic depolarization (AD) and failure of ion homeostasis play an important role in ischemia-induced neuronal injury. In the… 
1995
1995
Pharmacological protection against the cytotoxicity induced by 6-hydroxydopamine and H2O2 in chromaffin cells.
1994
1994
Effects of Ca2+ channel antagonists on chromaffin cell death and cytosolic Ca2+ oscillations induced by veratridine.
1992
1992
Effects of drugs on ventricular fibrillation and ischaemic K+ loss in a model of ischaemia in perfused guinea-pig hearts in vitro.
Highly Cited
1991
Highly Cited
1991
Myocardial protection by R 56865: a new principle based on prevention of ion channel pathology.
Intracellular Ca2+ overload is considered to be the final pathway leading to cell death under pathological conditions. However… 
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