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R 56865

Known as: R-56865, R56865 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (3)

BenzothiazolesCalcium Channel BlockersPiperidines

Papers overview

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Highly Cited
2000
Highly Cited
2000
Oxygen‐sensing persistent sodium channels in rat hippocampus
1 Persistent sodium channel activity was recorded before and during hypoxia from cell‐attached and inside‐out patches obtained… 
Review
1999
Review
1999
Drugs preventing Na+ and Ca2+ overload.
Cardiac intracellular Na+and Ca2+homeostasis is regulated by the concerted action of ion channels, pumps and exchangers. The Na… 
Highly Cited
1999
Highly Cited
1999
Ischemia/reperfusion-induced arrhythmias in anaesthetized rats: a role of Na+ and Ca2+ influx.
1995
1995
Pharmacological protection against the cytotoxicity induced by 6-hydroxydopamine and H2O2 in chromaffin cells.
1994
1994
Effects of Ca2+ channel antagonists on chromaffin cell death and cytosolic Ca2+ oscillations induced by veratridine.
1993
1993
R56865, a Na(+)- and Ca(2+)-overload inhibitor, reduces myocardial ischemia-reperfusion injury in blood-perfused rabbit hearts.
The cardioprotective effects of R56865 were studied in isolated rabbit hearts, blood-perfused with a support rabbit system. The… 
1991
1991
Block of the transient inward current by R56865 in guinea-pig ventricular myocytes.
1991
1991
Preferential block of the veratridine-induced, non-inactivating Na+ current by R56865 in single cardiac Purkinje cells.
1990
1990
Na+-activated K+ current in cardiac cells: rectification, open probability, block and role in digitalis toxicity
The Na+-activated K+ current was studied in inside-out patches and in whole cells isolated from the guinea-pig cardiac ventricle… 
1990
1990
R56865, a Potent New Antiarrhythmic Agent, Effective During Ischemia and Reperfusion in the Rat Heart
The antiarrhythmic effects of R56865 were characterized both in vivo and in vitro. Four groups (n = 12 per group) of anesthetized… 
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