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R 56865
Known as:
R-56865
, R56865
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (3)
Benzothiazoles
Calcium Channel Blockers
Piperidines
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2000
Highly Cited
2000
Oxygen‐sensing persistent sodium channels in rat hippocampus
A. Hammarström
,
P. Gage
Journal of Physiology
2000
Corpus ID: 41113175
1 Persistent sodium channel activity was recorded before and during hypoxia from cell‐attached and inside‐out patches obtained…
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Highly Cited
1999
Highly Cited
1999
Effect of Na+/Ca2+ exchange inhibitor, KB‐R7943 on ouabain‐induced arrhythmias in guinea‐pigs
T. Watano
,
Y. Harada
,
Kengo Harada
,
Noriyasu Nishimura
British Journal of Pharmacology
1999
Corpus ID: 12850038
We investigated protective effects of KB‐R7943, a Na+/Ca2+ exchange (NCX) inhibitor, on ouabain‐induced tonotropy and arrhythmias…
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Review
1999
Review
1999
Drugs preventing Na+ and Ca2+ overload.
U. Ravens
,
H. Himmel
Pharmacological Research
1999
Corpus ID: 24027728
Cardiac intracellular Na+and Ca2+homeostasis is regulated by the concerted action of ion channels, pumps and exchangers. The Na…
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Highly Cited
1999
Highly Cited
1999
Ischemia/reperfusion-induced arrhythmias in anaesthetized rats: a role of Na+ and Ca2+ influx.
H. R. Lu
,
P. Yang
,
P. Remeysen
,
A. Saels
,
D. Dai
,
F. De Clerck
European Journal of Pharmacology
1999
Corpus ID: 4532977
Highly Cited
1996
Highly Cited
1996
Effects of the Na+/H+-exchange inhibitor Hoe 642 on intracellular pH, calcium and sodium in isolated rat ventricular myocytes
U. Russ
,
C. Balser
,
+5 authors
H. Gögelein
Pflügers Archiv
1996
Corpus ID: 11043484
Abstract The inhibitors of the Na+/H+-exchange (NHE1) system Hoe 694 and Hoe 642 possess cardioprotective effects in ischaemia…
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Highly Cited
1995
Highly Cited
1995
Ion Channel Involvement in Anoxic Depolarization Induced by Cardiac Arrest in Rat Brain
Yaxia Xie
,
E. Zacharias
,
P. Hoff
,
F. Tegtmeier
Journal of Cerebral Blood Flow and Metabolism
1995
Corpus ID: 10854998
Anoxic depolarization (AD) and failure of ion homeostasis play an important role in ischemia-induced neuronal injury. In the…
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1995
1995
Pharmacological protection against the cytotoxicity induced by 6-hydroxydopamine and H2O2 in chromaffin cells.
F. Abad
,
R. Maroto
,
M. G. López
,
P. Sánchez-García
,
A. G. García
European Journal of Pharmacology
1995
Corpus ID: 32660247
1994
1994
Effects of Ca2+ channel antagonists on chromaffin cell death and cytosolic Ca2+ oscillations induced by veratridine.
R. Maroto
,
M. T. de la Fuente
,
+4 authors
A. G. García
European Journal of Pharmacology
1994
Corpus ID: 22518550
1992
1992
Effects of drugs on ventricular fibrillation and ischaemic K+ loss in a model of ischaemia in perfused guinea-pig hearts in vitro.
M. Gwilt
,
C. Henderson
,
J. Orme
,
J. D. Rourke
European Journal of Pharmacology
1992
Corpus ID: 25103967
Highly Cited
1991
Highly Cited
1991
Myocardial protection by R 56865: a new principle based on prevention of ion channel pathology.
L. Ver Donck
,
M. Borgers
American Journal of Physiology
1991
Corpus ID: 19629901
Intracellular Ca2+ overload is considered to be the final pathway leading to cell death under pathological conditions. However…
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