Pyroptosis

Known as: Inflammatory Apoptoses, Deaths, Pyroptotic Cell, Pyroptotic Cell Deaths 
A form of programmed cell death that occurs in immune cells in response to inflammation caused by microbial infections. The immune cells recognize… (More)
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Inflammasomes are intracellular complexes involved in the innate immunity that convert proIL-1β and proIL-18 to mature forms and… (More)
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Review
2017
Review
2017
Interleukin-1β (IL-1β) plays a central role in stimulation of innate immune system and inflammation and in several chronic… (More)
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Review
2017
Review
2017
Protease biology is intimately linked to the functional consequences of substrate cleavage events. Human caspases are a family of… (More)
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Review
2017
Review
2017
Pyroptosis is an inflammatory form of cell death that not only protects multicellular organisms from invading pathogenic bacteria… (More)
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Review
2017
Review
2017
Eukaryotic cells can die from physical trauma, which results in necrosis. Alternatively, they can die through programmed cell… (More)
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Highly Cited
2013
Highly Cited
2013
The pathway causing CD4 T-cell death in HIV-infected hosts remains poorly understood although apoptosis has been proposed as a… (More)
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Highly Cited
2010
Highly Cited
2010
Macrophages mediate crucial innate immune responses via caspase-1-dependent processing and secretion of interleukin 1β (IL-1… (More)
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Review
2009
Review
2009
Eukaryotic cells can initiate several distinct programmes of self-destruction, and the nature of the cell death process (non… (More)
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Highly Cited
2007
Highly Cited
2007
Shigella infection, the cause of bacillary dysentery, induces caspase-1 activation and cell death in macrophages, but the precise… (More)
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Highly Cited
2006
Highly Cited
2006
Salmonella enterica serovar Typhimurium invades host macrophages and induces a unique caspase-1-dependent pathway of cell death… (More)
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