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Pyrin Domain

Known as: PADD Domains, PAAD-DAPIN-PYRIN Domain, DAPIN Domains 
A protein interaction domain of the death domain superfamily. It is characterized by a 6-helix bundle similar to those that occur in DEATH DOMAIN… 
National Institutes of Health

Related topics

Related topics

3 relations
Pyrinaspects of radiation effectsphysiological aspects

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Meeting the Challenge of Identifying New Treatments for Type 2-low Neutrophilic Asthma.
2018
2018
3-(Naphthalen-2-yl(propoxy)methyl)azetidine hydrochloride attenuates NLRP3 inflammasome-mediated signaling pathway in lipopolysaccharide-stimulated BV2 microglial cells.
2018
2018
Bax Inhibitor-1 protects from Non-Alcoholic Steatohepatitis by limiting IRE 1 α signaling
France; Centre Hospitalier Universitaire Nice, Hôpital l’Archet, Département Digestif, 06200 Nice, France; Université Paris… 
2017
2017
A Novel Mutation in the Pyrin Domain of the NOD-like Receptor Family Pyrin Domain Containing Protein 3 in Muckle-Wells Syndrome
Background: Cryopyrin-associated periodic syndrome (CAPS) is a group of rare, heterogeneous autoinflammatory disease… 
2014
2014
Development of a cell-based assay system considering drug metabolism and immune- and inflammatory-related factors for the risk assessment of drug-induced liver injury.
2013
2013
NLRP 3 Inflammasome Knockout Mice are Protected Against Ischemic but not Cisplatin-Induced Acute Kidney Injury .
2011
2011
Cooperative Phosphoinositide and Peptide Binding by PSD-95/Discs Large/ZO-1 (PDZ) Domain of Polychaetoid, Drosophila Zonulin*
Background: PDZ domains mediate protein interaction but may also sense lipid signaling. Results: We characterized a new… 
2009
2009
Kinetic properties of ASC protein aggregation in epithelial cells
Apoptosis‐associated speck‐like protein with CARD domain (ASC), an adaptor protein composed of caspase recruitment and pyrin… 
Review
2007
Review
2007
The Death Domain Superfamily in Intracellular Signaling of Apoptosis and Inflammation
The death domain (DD) superfamily comprising the death domain (DD) subfamily, the death effector domain (DED) subfamily, the… 
Highly Cited
2001
Highly Cited
2001
Prevalence and significance of the familial Mediterranean fever gene mutation encoding pyrin Q148.
Familial Mediterranean fever (FMF) is caused by more than 25 mutations in the gene MEFV, which encodes pyrin (marenostrin), a… 
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