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Pyrin Domain

Known as: PADD Domains, PAAD-DAPIN-PYRIN Domain, DAPIN Domains 
A protein interaction domain of the death domain superfamily. It is characterized by a 6-helix bundle similar to those that occur in DEATH DOMAIN… 
National Institutes of Health

Related topics

Related topics

3 relations
Pyrinaspects of radiation effectsphysiological aspects

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Meeting the Challenge of Identifying New Treatments for Type 2-low Neutrophilic Asthma.
2015
2015
Cellulose nanocrystal cationic derivative induces NLRP3 inflammasome-dependent IL-1β secretion associated with mitochondrial ROS production
2014
2014
Berberine prevents damage to the intestinal mucosal barrier during early phase of sepsis in rat through mechanisms independent of the NOD-like receptors signaling pathway.
2014
2014
Development of a cell-based assay system considering drug metabolism and immune- and inflammatory-related factors for the risk assessment of drug-induced liver injury.
2014
2014
Reduction of IL-17A Might Suppress the Th1 Response and Promote the Th2 Response by Boosting the Function of Treg Cells during Silica-Induced Inflammatory Response In Vitro
Silica inhalation can induce chronic lung inflammation and fibrosis. Upon silica stimulation, activated macrophages trigger the T… 
Highly Cited
2013
Highly Cited
2013
Correlates of long-term participation in a physical activity-based positive youth development program for low-income youth: sustained involvement and psychosocial outcomes.
2011
2011
Cooperative Phosphoinositide and Peptide Binding by PSD-95/Discs Large/ZO-1 (PDZ) Domain of Polychaetoid, Drosophila Zonulin*
Background: PDZ domains mediate protein interaction but may also sense lipid signaling. Results: We characterized a new… 
Highly Cited
2009
Highly Cited
2009
The presence of aberrant DNA methylation in noncancerous esophageal mucosae in association with smoking history
Esophageal squamous cell carcinomas (ESCCs) tend to have multiple primary lesions, and it is believed that they arise from… 
Highly Cited
2003
Highly Cited
2003
Caspy, a Zebrafish Caspase, Activated by ASC Oligomerization Is Required for Pharyngeal Arch Development*
The pyrin domain was identified recently in multiple proteins that are associated with apoptosis and/or inflammation, but the… 
Highly Cited
2001
Highly Cited
2001
Prevalence and significance of the familial Mediterranean fever gene mutation encoding pyrin Q148.
Familial Mediterranean fever (FMF) is caused by more than 25 mutations in the gene MEFV, which encodes pyrin (marenostrin), a… 
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