Pyrin

Known as: TRIM20 Protein, MEFV Protein, Pyrin [Chemical/Ingredient] 
A tripartite motif protein that consists of an N-terminal pyrin domain, a central coiled-coil region and B-box type ZINC FINGER, and C-terminal… (More)
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Mutations in cryopyrin and pyrin proteins are responsible for several autoinflammatory disorders in humans, suggesting that these… (More)
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Highly Cited
2006
Highly Cited
2006
Familial Mediterranean fever (FMF) is a recessively inherited autoinflammatory disorder with high carrier frequencies in the… (More)
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Review
2006
Review
2006
Innate immunity to microorganisms in mammals has gained a substantial interest during the last decade. The discovery of the Toll… (More)
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Highly Cited
2003
Highly Cited
2003
Pyrin, the familial Mediterranean fever protein, is found in association with the cytoskeleton in myeloid/monocytic cells and… (More)
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Highly Cited
2003
Highly Cited
2003
Familial Mediterranean fever (FMF) is an inherited disorder characterized by recurrent episodes of fever and inflammation. Most… (More)
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Highly Cited
2002
Highly Cited
2002
The PYRIN and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large… (More)
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Highly Cited
2001
Highly Cited
2001
Patients with familial Mediterranean fever suffer sporadic inflammatory attacks characterized by fever and intense pain (in… (More)
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Review
2000
Review
2000
Modular protein-protein interaction domains play an important role in many intracellular signal transduction pathways. In… (More)
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Review
1998
Review
1998
Familial Mediterranean fever (FMF) is a genetic disorder, restricted to peoples originating in the Middle East. The clinical… (More)
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Highly Cited
1998
Highly Cited
1998
Accurate multiple alignments of 86 domains that occur in signaling proteins have been constructed and used to provide a Web-based… (More)
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