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Pyrilamine

Known as: N-(P-Methoxybenzyl)-n',n'-dimethyl-N-(alpha-pyridyl)ethylenediamine, Mepyramine, N-[(4-Methoxyphenyl)methyl]-n',n'-dimethyl-N-2-pyridinyl-1,2-ethanediamine 
A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both… 
National Institutes of Health

Related topics

Related topics

35 relations

Narrower (9)

3-iodo-4-azidophenpyramineAnthisanBoots Bite & Sting ReliefPoly D
Acetaminophen 500 MG / Caffeine 60 MG / Pyrilamine Maleate 15 MG Oral Tablet [Midol Complete]Acetaminophen 500 MG / pamabrom 25 MG / Pyrilamine Maleate 15 MG Oral TabletAcetaminophen 500 MG / pamabrom 25 MG / Pyrilamine Maleate 15 MG Oral Tablet [Premsyn PMS]Allergic Conjunctivitis

Broader (4)

AminopyrineAnti-Allergic AgentsHistamine H1 AntagonistsSleep Aids, Pharmaceutical

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1991
Highly Cited
1991
Pituitary adenylate cyclase activating peptide (PACAP) in guinea-pig lung: distribution and dilatory effects
Highly Cited
1987
Highly Cited
1987
Allosteric Interaction Between the Site Labeled by [3H]Imipramine and the Serotonin Transporter in Human Platelets
Abstract: The nature of interaction between the site labeled by [3H]imipramine (IMI) and the 5‐hydroxytryptamine (5‐HT, serotonin… 
Review
1985
Review
1985
Analgesic effects of antihistaminics.
Highly Cited
1984
Highly Cited
1984
The platelet‐independent release of thromboxane A2 by Paf‐acether from guinea‐pig lungs involves mechanisms distinct from those for leukotriene
1 Intra‐arterial injections of platelet‐activating factor (Paf‐acether, 10–300 ng) to the perfused guinea‐pig lung induced a dose… 
Highly Cited
1984
Highly Cited
1984
Histamine Stimulation of Inositol 1‐Phosphate Accumulation in Lithium‐Treated Slices from Regions of Guinea Pig Brain
Abstract: Histamine stimulated the accumulation of [3H]inositol 1‐phosphate in the presence of 10 mM LiCl in [3H]inositol‐loaded… 
Review
1983
Review
1983
Histamine and the hypothalamus
Highly Cited
1981
Highly Cited
1981
Human C5a des Arg increases vascular permeability.
C5a were generated in human plasma by incubation with zymosan in the presence of a carboxypeptidase B inhibitor. The… 
Highly Cited
1979
Highly Cited
1979
Effect of neurotransmitters on the in vitro release of immunoreactive thyrotropin-releasing hormone from rat mediobasal hypothalamus.
The in vitro release of TRH from hypothalamic fragments or purified nerve endings (synaptosomes) has been evaluated after… 
Highly Cited
1975
Highly Cited
1975
Drugs affecting the synthesis of glycerides and phospholipids in rat liver. The effects of clofibrate, halofenate, fenfluramine, amphetamine, cinchocaine, chlorpromazine, demethylimipramine…
The effects on glycerolipid synthesis of a series of compounds including many drugs were investigated in cell-free preparations… 
Highly Cited
1968
Highly Cited
1968
Atropine‐resistant longitudinal muscle spasms due to excitation of non‐cholinergic neurones in Auerbach's plexus
1. In accordance with the dual histology of Auerbach's plexus (Dogiel, 1899; Hill, 1927) two types of neurone can be shown to be… 
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