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Pyrilamine

Known as: N-(P-Methoxybenzyl)-n',n'-dimethyl-N-(alpha-pyridyl)ethylenediamine, Mepyramine, N-[(4-Methoxyphenyl)methyl]-n',n'-dimethyl-N-2-pyridinyl-1,2-ethanediamine 
A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both… 
National Institutes of Health

Related topics

Related topics

35 relations

Narrower (9)

3-iodo-4-azidophenpyramineAnthisanBoots Bite & Sting ReliefPoly D
Acetaminophen 500 MG / Caffeine 60 MG / Pyrilamine Maleate 15 MG Oral Tablet [Midol Complete]Acetaminophen 500 MG / pamabrom 25 MG / Pyrilamine Maleate 15 MG Oral TabletAcetaminophen 500 MG / pamabrom 25 MG / Pyrilamine Maleate 15 MG Oral Tablet [Premsyn PMS]Allergic Conjunctivitis

Broader (4)

AminopyrineAnti-Allergic AgentsHistamine H1 AntagonistsSleep Aids, Pharmaceutical

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1988
1988
Selective inhibition of arachidonate 5‐lipoxygenase by novel acetohydroxamic acids: effects on bronchial anaphylaxis in anaesthetized guinea‐pigs
1 The effect of a novel series of orally‐active acetohydroxamic acid inhibitors of arachidonate 5‐lipoxygenase on ‘leukotriene… 
1986
1986
Enhancement of plasma levels of biologically active leukotriene B compounds during anaphylaxis in guinea pigs pretreated by indomethacin or by a fish oil-enriched diet.
The changes in arterial plasma concentrations of immunoreactive leukotriene B (LTB) were compared after antigen challenge of two… 
1985
1985
The effects of autacoids on cloned murine lymphoid cells: modulation of IL 2 secretion and the activity of natural suppressor cells.
The pharmacologic effects of histamine and isoproterenol (autacoids) were studied on clones of murine T helper (TH) and natural… 
1981
1981
Angiotensin‐Induced Release of a Prostacyclin‐Like Substance from the Lungs
Summary: Intravenous infusions of angiotensins I and II into anesthetized dogs caused release of a prostacyclin-like substance… 
Highly Cited
1980
Highly Cited
1980
Vasodilatation in the dental pulp produced by electrical stimulation of the inferior alveolar nerve in the cat.
The effects of nerve stimulation on blood flow were studied in the dental pulp of anesthetized cats. Changes in iodide… 
Highly Cited
1977
Highly Cited
1977
Factors controlling the activities of phosphatidate phosphohydrolase and phosphatidate cytidylyltransferase. The effects of chlorpromazine, demethylimipramine, cinchocaine, norfenfluramine…
1. Microsomal membranes from rat liver were incubated with ATP, CoA, Mg2+, [14C]palmitate, F- and sn-glycerol 3-phosphate in… 
Highly Cited
1975
Highly Cited
1975
Drugs affecting the synthesis of glycerides and phospholipids in rat liver. The effects of clofibrate, halofenate, fenfluramine, amphetamine, cinchocaine, chlorpromazine, demethylimipramine…
The effects on glycerolipid synthesis of a series of compounds including many drugs were investigated in cell-free preparations… 
1967
1967
Biological characterization of mouse 'early' antibodies.
The ability of mouse antiserum obtained early after immunization to induce passive cutaneous anaphylaxis (PCA) using a short (4… 
1966
1966
Increased permeability of the capillaries of the rat heart to the plasma albumin with asphyxiation and with perfusion
1. Studies on the rate of efflux from the isolated perfused rat heart of plasma albumin conjugated with Evans Blue showed the… 
1966
1966
The effects of potassium ions and denervation on protein synthesis and the transport of amino acids in muscle.
1. The effects of varying concentrations of K(+) during incubation, of denervation and of various drugs on the accumulation of…