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Pyrilamine

Known as: N-(P-Methoxybenzyl)-n',n'-dimethyl-N-(alpha-pyridyl)ethylenediamine, Mepyramine, N-[(4-Methoxyphenyl)methyl]-n',n'-dimethyl-N-2-pyridinyl-1,2-ethanediamine 
A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both… 
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
Summary1.Antidromic vasodilation and neurogenic plasma extravasation were induced by antidromic stimulation of the saphenous… 
Highly Cited
1993
Highly Cited
1993
1 Endotoxin induces nitric oxide synthase in vascular tissue, including rat main pulmonary artery. Currently available agents… 
Highly Cited
1988
Highly Cited
1988
A rational approach to the design of centrally acting agents is presented, based initially upon a comparison of the… 
Highly Cited
1988
Highly Cited
1988
Recent evidence suggests that activation of airway C-fibers, besides causing afferent transmission, also causes release of… 
Highly Cited
1988
Highly Cited
1986
Highly Cited
1986
Several N-benzylpiperazino derivatives of [1]benzopyrano[2,3-d]-1,2,3-triazol-9(1H)-one and its 5-methyl homologue have been… 
Highly Cited
1984
Highly Cited
1984
Abstract: Characterisation of receptor‐mediated breakdown of inositol phospholipids in rat cortical slices has been performed… 
Highly Cited
1983
Highly Cited
1983
Electrical stimulation of the cervical vagus nerve in anesthetized guinea pigs induced a rapid increase in respiratory… 
Highly Cited
1971
Highly Cited
1971
1 The time course of oedema formation in rats caused by injection of carrageenin into the paw was followed for 5·5 hours. Intact… 
Highly Cited
1966
Highly Cited
1966
  • A. Ash, H. Schild
  • British journal of pharmacology and chemotherapy
  • 1966
  • Corpus ID: 42579739
Heinz Schild's fascination with the pharmacology of histamine started in 1934 when he studied (with de Burgh Daly at Edinburgh…