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Pyrilamine

Known as: N-(P-Methoxybenzyl)-n',n'-dimethyl-N-(alpha-pyridyl)ethylenediamine, Mepyramine, N-[(4-Methoxyphenyl)methyl]-n',n'-dimethyl-N-2-pyridinyl-1,2-ethanediamine 
A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both… 
National Institutes of Health

Related topics

Related topics

35 relations

Narrower (9)

3-iodo-4-azidophenpyramineAnthisanBoots Bite & Sting ReliefPoly D
Acetaminophen 500 MG / Caffeine 60 MG / Pyrilamine Maleate 15 MG Oral Tablet [Midol Complete]Acetaminophen 500 MG / pamabrom 25 MG / Pyrilamine Maleate 15 MG Oral TabletAcetaminophen 500 MG / pamabrom 25 MG / Pyrilamine Maleate 15 MG Oral Tablet [Premsyn PMS]Allergic Conjunctivitis

Broader (4)

AminopyrineAnti-Allergic AgentsHistamine H1 AntagonistsSleep Aids, Pharmaceutical

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1993
Highly Cited
1993
Aminoguanidine selectively inhibits inducible nitric oxide synthase
1 Endotoxin induces nitric oxide synthase in vascular tissue, including rat main pulmonary artery. Currently available agents… 
Highly Cited
1988
Highly Cited
1988
Release of multiple tachykinins from capsaicin-sensitive sensory nerves in the lung by bradykinin, histamine, dimethylphenyl piperazinium, and vagal nerve stimulation.
Recent evidence suggests that activation of airway C-fibers, besides causing afferent transmission, also causes release of… 
Highly Cited
1988
Highly Cited
1988
Studies on the mechanism of ethanol-induced gastric damage in rats.
Highly Cited
1988
Highly Cited
1988
Early and late-phase bronchoconstriction after allergen challenge of nonanesthetized guinea pigs. I. The association of disordered airway physiology to leukocyte infiltration.
We describe a guinea pig model of asthma in which animals were sensitized and challenged by inhalation of aerosolized ovalbumin… 
Highly Cited
1984
Highly Cited
1984
Inositol Phospholipid Hydrolysis in Rat Cerebral Cortical Slices: I. Receptor Characterisation
Abstract: Characterisation of receptor‐mediated breakdown of inositol phospholipids in rat cortical slices has been performed… 
Highly Cited
1983
Highly Cited
1983
A substance P antagonist inhibits vagally induced increase in vascular permeability and bronchial smooth muscle contraction in the guinea pig.
Electrical stimulation of the cervical vagus nerve in anesthetized guinea pigs induced a rapid increase in respiratory… 
Highly Cited
1979
Highly Cited
1979
Substance P as neurogenic mediator of antidromic vasodilation and neurogenic plasma extravasation
Summary1.Antidromic vasodilation and neurogenic plasma extravasation were induced by antidromic stimulation of the saphenous… 
Highly Cited
1977
Highly Cited
1977
Receptors for bradykinin in rabbit aortae.
Rabbit aorta strips respond to bradykinin (BK) and to the C-terminal fragment of BK, the octapeptide 1-8 BK (Octa) with sustained… 
Highly Cited
1971
Highly Cited
1971
Mediators of the inflammation induced in the rat paw by carrageenin
1 The time course of oedema formation in rats caused by injection of carrageenin into the paw was followed for 5·5 hours. Intact… 
Highly Cited
1971
Highly Cited
1971
Cutaneous reactions to intradermal prostaglandins
1 The effects of intradermally injected prostaglandins (PGs) E1, E2, F1α and F2α have been examined in the rat and in man. 2 PGE1… 
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