Pyrilamine

Known as: N-(P-Methoxybenzyl)-n',n'-dimethyl-N-(alpha-pyridyl)ethylenediamine, Mepyramine, N-[(4-Methoxyphenyl)methyl]-n',n'-dimethyl-N-2-pyridinyl-1,2-ethanediamine 
A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1947-2018
05010019472017

Papers overview

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Highly Cited
2004
Highly Cited
2004
The role of histamine H(1), H(2), H(3) and H(4) receptors in acute itch induced by histamine was investigated in female BalbC… (More)
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Highly Cited
1996
Highly Cited
1996
We have demonstrated previously the importance of histaminergic neurons in arousal mechanisms. In addition to their ascending… (More)
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Highly Cited
1993
Highly Cited
1993
1. Endotoxin induces nitric oxide synthase in vascular tissue, including rat main pulmonary artery. Currently available agents… (More)
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Highly Cited
1993
Highly Cited
1993
Intraperitoneal administration of some flavonoids (apigenin, flavone, kaempferol, morin, myricetin, naringin and rutin; 12.5-50… (More)
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Highly Cited
1988
Highly Cited
1988
Polygraphic 23-hr recordings were carried out in 25 adult cats in order to examine the effects of both systemic and local… (More)
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Highly Cited
1988
Highly Cited
1988
Recent evidence suggests that activation of airway C-fibers, besides causing afferent transmission, also causes release of… (More)
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Highly Cited
1987
Highly Cited
1987
We previously described the cross-resistance patterns and cellular pharmacology of a human leukemic cell line, CEM/VM-1, selected… (More)
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Highly Cited
1986
Highly Cited
1986
Multiple drug resistance of tumor cells is a common problem in cancer therapy. We have demonstrated that membrane vesicles from… (More)
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Highly Cited
1979
Highly Cited
1979
1. Antidromic vasodilation and neurogenic plasma extravasation were induced by antidromic stimulation of the saphenous nerve in… (More)
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Highly Cited
1971
Highly Cited
1971
1. The time course of oedema formation in rats caused by injection of carrageenin into the paw was followed for 5.5 hours. Intact… (More)
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