Purinethiol
National Institutes of Health
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Several nontoxic purinethiols have been shown to block the ability of the carcinogen 7-r,8-t-dihydroxy-9-t,10-t-oxy-7,8,9,10…
The chemotherapeutic agent 6-mercaptopurine was previously shown to inhibit the binding of 7r,8t-dihydroxy-9,10t-oxy-7,8,9,10…
Delayed growth arrest was observed in HL-60 acute promyelocytic leukemia cells after exposure to 6-thioguanine (TG). This growth…
Summary Two purinethiol nucleosides, α-2′-deoxythioguanosine and arabinosyl-6-mercaptopurine, suppress the homograft response in…
Summary The capacity of several purinethiol derivatives to produce prolongation of survival in mice bearing ascites-cell tumors…