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Proto-Oncogene Proteins p21(ras)
Known as:
ras, Proto-Oncogene Protein
, c-ras, p21
, Proteins c-ras, Proto-Oncogene
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Cellular proteins encoded by the H-ras, K-ras and N-ras genes. The proteins have GTPase activity and are involved in signal transduction as monomeric…
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National Institutes of Health
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Related topics
Related topics
26 relations
Costello syndrome (disorder)
GTP Binding
GTP Binding Domain
Genes, ras
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Narrower (8)
HRAS protein, human
K-Ras4B protein, human
KRAS protein, human
KRAS4B protein, mouse
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Detection of K-Ras oncogene using magnetic beads-quantum dots in microfluidic chip.
H. Noh
,
Jong Sung Kim
Journal of Nanoscience and Nanotechnology
2013
Corpus ID: 23647469
Recently quantum dots (QDs) have been extensively used in the field of biotechnology. QDs have merits of wide selection of…
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2007
2007
Protein kinase C delta is required for survival of cells expressing activated p21RAS.
Shuhua Xia
,
L. Forman
,
D. Faller
Journal of Biological Chemistry
2007
Corpus ID: 43880544
Inhibition of protein kinase C (PKC) activity in transformed cells and tumor cells containing activated p21(RAS) results in…
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2006
2006
Involvement of protein kinase C alpha (PKC alpha) in the early action of angiotensin II type 2 (AT2) effects on neurite outgrowth in NG108-15 cells: AT2-receptor inhibits PKC alpha and p21ras…
H. Beaudry
,
L. Gendron
,
Marie‐Odile Guimond
,
M. Payet
,
N. Gallo‐Payet
Endocrinology
2006
Corpus ID: 25942805
The aim of the present study was to investigate whether protein kinase C (PKC) isoforms may be among the putative candidates…
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2005
2005
beta-catenin signaling and regulation of cyclin D1 promoter in NRK-49F cells transformed by down-regulation of the tumor suppressor lysyl oxidase.
M. Giampuzzi
,
R. Oleggini
,
C. Albanese
,
R. Pestell
,
A. Di Donato
Biochimica et Biophysica Acta
2005
Corpus ID: 12851426
2001
2001
Localizing a Control Region in the Pathway to Leukotriene C4 Secretion Following Stimulation of Human Basophils with Anti-IgE Antibody1
K. Miura
,
S. Lavens-Phillips
,
D. MacGlashan
Journal of Immunology
2001
Corpus ID: 10498345
Mediator release from human basophils is a self-limited process, but down-regulation of the signaling cascades leading to…
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Highly Cited
2000
Highly Cited
2000
Ras Mediates Effector Pathways Responsible for Pre-B Cell Survival, Which Is Essential for the Developmental Progression to the Late Pre-B Cell Stage
H. Nagaoka
,
Yoshimasa Takahashi
,
+13 authors
T. Takemori
Journal of Experimental Medicine
2000
Corpus ID: 17985476
Ras is essential for the transition from early B cell precursors to the pro-B stage, and is considered to be involved in the…
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2000
2000
Anti-K-ras1 Ribozyme Adenoviral Vector for Gene Therapy of Non-Small Cell Lung Cancer.
Y. Zhang
,
J. Nemunaitis
,
A. Tong
Methods in Molecular Medicine
2000
Corpus ID: 207391851
Lung cancer is the leading cause of cancer death for men and women in the United States. Several factors affect survival in…
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1999
1999
H-Ras is involved in the inside-out signaling pathway of interleukin-3-induced integrin activation.
H. Shibayama
,
N. Anzai
,
S. Braun
,
S. Fukuda
,
C. Mantel
,
H. Broxmeyer
Blood
1999
Corpus ID: 22300487
The proto-oncogene product, p21(ras), has been implicated in the cellular mechanism of adhesion, although its precise role has…
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1997
1997
Nucleotide Hydrolysis-dependent Conformational Changes in p21 ras as Studied Using ESR Spectroscopy*
Michael Haller
,
U. Hoffmann
,
Thomas Schanding
,
R. Goody
,
P. Vogel
Journal of Biological Chemistry
1997
Corpus ID: 35247014
We have employed ESR spectroscopy using guanine nucleotides that contain a spin label at the 2′,3′-position of the ribose to…
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1996
1996
The p21(RAS) farnesyltransferase alpha subunit in TGF-beta and activin signaling.
T. Wang
,
P. Danielson
,
B. Y. Li
,
P. C. Shah
,
S. D. Kim
,
P. Donahoe
Science
1996
Corpus ID: 24133354
The alpha subunit of p21(RAS) farnesyltransferase (FNTA), which is also shared by geranylgeranyltransferase, was isolated as a…
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