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Protein Unc-119 Homolog A

Known as: Retinal Protein 4, hRG4 
Protein unc-119 homolog A (240 aa, ~27 kDa) is encoded by the human UNC119 gene. This protein plays a role in subcellular protein localization.
National Institutes of Health

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11 relations
Cellular MembraneCentrosomeLigand BindingMolecular Transport

Papers overview

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2019
2019
Whole‐exome sequencing identified ARL2 as a novel candidate gene for MRCS (microcornea, rod‐cone dystrophy, cataract, and posterior staphyloma) syndrome
Adenosine diphosphate (ADP)‐ribosylation factor‐like 2 (ARL2) protein participates in a broad range of cellular processes and… 
2011
2011
Interaction of Transducin with Uncoordinated 119 Protein (UNC119)
The key visual G protein, transducin undergoes bi-directional translocations between the outer segment (OS) and inner… 
Highly Cited
2008
Highly Cited
2008
Specificity of Arl2/Arl3 signaling is mediated by a ternary Arl3‐effector‐GAP complex
2007
2007
Targeted inactivation of synaptic HRG4 (UNC119) causes dysfunction in the distal photoreceptor and slow retinal degeneration, revealing a new function.
2006
2006
Molecular approach to annelid regeneration: cDNA subtraction cloning reveals various novel genes that are upregulated during the large‐scale regeneration of the oligochaete, Enchytraeus japonensis
To identify genes specifically activated during annelid regeneration, suppression subtractive hybridization was performed with… 
2005
2005
Mutation in HRG4 (UNC119) Leads To Mitochondrial ANT1–Mediated Apoptosis and Retinal Degeneration
2002
2002
The ABCA4 gene in autosomal recessive cone-rod dystrophies.
To the Editor: Recently, Maugeri et al. (2000) reported on the screening of the ABCA4 gene in 5 patients with autosomal… 
2002
2002
Changes in retinal synaptic proteins in the transgenic model expressing a mutant HRG4 (UNC119).
PURPOSE HRG4 (UNC119) is a photoreceptor synaptic protein, a truncation mutant of which has been shown to cause late-onset cone… 
1999
1999
Characterization of the gene for HRG4 (UNC119), a novel photoreceptor synaptic protein homologous to unc-119.
HRG4 (HGMW-approved symbol UNC119) is a novel human photoreceptor-enriched gene coding for a 240-amino-acid protein. Initially… 
Highly Cited
1997
Highly Cited
1997
Characterization of mouse and human nude genes
Abstract The differentiation of primitive epithelial precursor cells in the thymic primordium into subcapsular, cortical, and… 
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