Protein Tyrosine Phosphatase, Receptor-Type, N

Nutrients and growth hormones promote insulin production and the proliferation of pancreatic β-cells. An imbalance between ever… Expand

BACKGROUND There is an increase in the incidence of type 2 diabetes in children and adolescents. Absence of known diabetes… Expand

Islet cell autoantigen (ICA) 512 is a receptor‐tyrosine phosphatase‐like protein associated with the secretory granules of… Expand

We report the identification of βIV spectrin, a novel spectrin isolated as an interactor of the receptor tyrosine phosphatase… Expand

It has been reported that there is a heterogeneity in the clinical course of Japanese patients with type 1 diabetes. To elucidate… Expand

The related tyrosine phosphatase-like proteins, islet cell antigen 512 (ICA512) and phosphatase homologue in granules of… Expand

Antibodies to islet cell proteins detected as 37,000 and 40,000 Mr tryptic fragments (37- and 40-kDa antigens) are strongly… Expand

The majority of patients with insulin-dependent diabetes (IDDM) have Abs to 40- and/or 37-kDa tryptic fragments (37/40K-Abs… Expand

As part of a general program of screening islet expression libraries we have identified a clone from a λgt11 human islet… Expand

The presence of serum islet cell cytoplasmic antibodies (ICAs) is a standard autoimmune marker for insulin-dependent diabetes… Expand