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Protein Tyrosine Phosphatase, Receptor-Type, N

Known as: Protein Tyrosine Phosphatase, Receptor Type N, PTPase IA2, Insulinoma Associated Protein 2 
National Institutes of Health

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Related topics

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PTPRN gene

Papers overview

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Highly Cited
2006
Highly Cited
2006
Synergy of glucose and growth hormone signalling in islet cells through ICA512 and STAT5
Nutrients and growth hormones promote insulin production and the proliferation of pancreatic β-cells. An imbalance between ever… 
Highly Cited
2006
Highly Cited
2006
Initial results of screening of nondiabetic organ donors for expression of islet autoantibodies.
CONTEXT Type 1A diabetes is characterized by a long prodromal phase during which autoantibodies to islet antigens are present… 
Highly Cited
2001
Highly Cited
2001
Diabetic autoimmune markers in children and adolescents with type 2 diabetes.
BACKGROUND There is an increase in the incidence of type 2 diabetes in children and adolescents. Absence of known diabetes… 
Highly Cited
2000
Highly Cited
2000
βiv Spectrin, a New Spectrin Localized at Axon Initial Segments and Nodes of Ranvier in the Central and Peripheral Nervous System
We report the identification of βIV spectrin, a novel spectrin isolated as an interactor of the receptor tyrosine phosphatase… 
Highly Cited
1999
Highly Cited
1999
Autoantibodies to multiple islet autoantigens in patients with abrupt onset type 1 diabetes and diabetes diagnosed with urinary glucose screening.
It has been reported that there is a heterogeneity in the clinical course of Japanese patients with type 1 diabetes. To elucidate… 
Highly Cited
1998
Highly Cited
1998
Definition of multiple ICA512/phogrin autoantibody epitopes and detection of intramolecular epitope spreading in relatives of patients with type 1 diabetes.
The related tyrosine phosphatase-like proteins, islet cell antigen 512 (ICA512) and phosphatase homologue in granules of… 
Highly Cited
1996
Highly Cited
1996
Identification of the 37-kDa Antigen in IDDM as a Tyrosine Phosphatase-Like Protein (Phogrin) Related to IA-2
Antibodies to islet cell proteins detected as 37,000 and 40,000 Mr tryptic fragments (37- and 40-kDa antigens) are strongly… 
Highly Cited
1995
Highly Cited
1995
Identification of protein tyrosine phosphatase-like IA2 (islet cell antigen 512) as the insulin-dependent diabetes-related 37/40K autoantigen and a target of islet-cell antibodies.
The majority of patients with insulin-dependent diabetes (IDDM) have Abs to 40- and/or 37-kDa tryptic fragments (37/40K-Abs… 
Highly Cited
1995
Highly Cited
1995
ICA512 Autoantibody Radioassay
As part of a general program of screening islet expression libraries we have identified a clone from a λgt11 human islet… 
Highly Cited
1995
Highly Cited
1995
Pancreatic Islet Cell Cytoplasmic Antibody in Diabetes is Represented by Antibodies to Islet Cell Antigen 512 and Glutamic Acid Decarboxylase
The presence of serum islet cell cytoplasmic antibodies (ICAs) is a standard autoimmune marker for insulin-dependent diabetes… 
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