Protein D-Aspartate-L-Isoaspartate Methyltransferase

Known as: Methyltransferase, Protein L-Isoaspartyl, Protein D-Aspartate-L-Isoaspartate Methyltransferase [Chemical/Ingredient], Gene Product, pcm 
A PROTEIN O-METHYLTRANSFERASE that recognizes and catalyzes the methyl esterification of ISOASPARTIC ACID and D-ASPARTIC ACID residues in peptides… (More)
National Institutes of Health

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In BloodPCMT1 geneProcess of secretionantagonists & inhibitors
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PCMT1 protein, human

Papers overview

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Highly Cited
2012
Highly Cited
2012
Chromatin modifying enzymes as modulators of reprogramming
Generation of induced pluripotent stem cells (iPSCs) by somatic cell reprogramming involves global epigenetic remodelling… (More)
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Review
2008
Review
2008
Phosphatidylcholine and choline homeostasis.
Phosphatidylcholine (PC) is made in mammalian cells from choline via the CDP-choline pathway. Animals obtain choline primarily… (More)
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Highly Cited
2004
Highly Cited
2004
Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus.
The cellular function of the menin tumor suppressor protein, product of the MEN1 gene mutated in familial multiple endocrine… (More)
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Highly Cited
2003
Highly Cited
2003
A haplotype implicated in schizophrenia susceptibility is associated with reduced COMT expression in human brain.
The gene encoding catechol-O-methyltransferase (COMT) is a strong candidate for schizophrenia susceptibility, owing to the role… (More)
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Highly Cited
2000
Highly Cited
2000
NMDA spikes in basal dendrites of cortical pyramidal neurons
Basal dendrites are a major target for synaptic inputs innervating cortical pyramidal neurons. At present little is known about… (More)
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Highly Cited
1999
Highly Cited
1999
Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity
Accumulation of the amyloid-β protein (Aβ) in the cerebral cortex is an early and invariant event in the pathogenesis of… (More)
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1994
1994
Repair of spontaneously deamidated HPr phosphocarrier protein catalyzed by the L-isoaspartate-(D-aspartate) O-methyltransferase.
The non-enzymatic deamidation at residues Asn-12 and Asn-38 of Escherichia coli phosphocarrier protein, HPr, and the repair of… (More)
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Highly Cited
1993
Highly Cited
1993
Structural alterations in the peptide backbone of beta-amyloid core protein may account for its deposition and stability in Alzheimer's disease.
The structure of beta-amyloid (beta A) from Alzheimer disease brains was examined to determine if post-translational… (More)
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Highly Cited
1990
Highly Cited
1990
Structure-activity relationships for amino acid transmitter candidates acting at N-methyl-D-aspartate and quisqualate receptors.
Dose-response curves for activation of excitatory amino acid receptors on mouse embryonic hippocampal neurons in culture were… (More)
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Highly Cited
1987
Highly Cited
1987
Macrophage synthesis of nitrite, nitrate, and N-nitrosamines: precursors and role of the respiratory burst.
The macrophage cell line RAW 264.7 when activated with Escherichia coli lipopolysaccharide and interferon-gamma synthesized… (More)
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