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Protein C Deficiency

Known as: Hereditary Thrombophilia Due To Protein C Deficiency, Protein C Deficiencies, c protein deficiency 
An absence or deficiency in PROTEIN C which leads to impaired regulation of blood coagulation. It is associated with an increased risk of severe or… 
National Institutes of Health

Related topics

Related topics

14 relations
Activated Protein C ResistanceCONGENITAL DISORDER OF GLYCOSYLATION, TYPE IeCongenital Bleeding DisorderHematopoietic and Lymphoid Cell

Narrower (2)

THROMBOPHILIA DUE TO PROTEIN C DEFICIENCY, AUTOSOMAL RECESSIVEThrombophilia, Hereditary, Due To Protein C Deficiency, Autosomal Dominant

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1998
1998
A preliminary pilot study of treatment of thrombophilia and hypofibrinolysis and amelioration of the pain of osteonecrosis of the jaws.
Highly Cited
1997
Highly Cited
1997
Paediatric thrombo-embolism: the influence of non-genetic factors and the role of activated protein C resistance and protein C deficiency
Abstract In many children, the pathogenesis of thrombo-embolism remains unexplained. This study examines the role of non-genetic… 
Highly Cited
1997
Highly Cited
1997
ProC Global: the first functional screening assay for the complete protein C pathway.
In clinical practice, venous thromboembolic complications are much more frequent than bleeding disorders. In fact, disturbances… 
1996
1996
Genetic Characterization of Protein C Deficiency in Japanese Subjects Using a Rapid and Nonradioactive Method for Single-Strand Conformational Polymorphism Analysis and a Model Building
Summary We studied the molecular basis of protein C deficiency in 28 Japanese families including 4 asymptomatic families. Two… 
1994
1994
Three Missense Mutations in the Protein C Heavy Chain Causing Type I and Type II Protein C Deficiency
Summary We have studied the molecular basis of protein C deficiency in three families with a history of thromboembolic disease… 
1993
1993
Normalization of markers of coagulation activation with a purified protein C concentrate in adults with homozygous protein C deficiency
Homozygous or double heterozygous protein-C deficiency can present at birth with purpura fulminans or later in life with venous… 
1993
1993
Twelve novel and two recurrent mutations in 14 Austrian families with hereditary protein C deficiency
The molecular basis of hereditary type I and type II protein C deficiency was studied in a panel of 14 unrelated Austrian… 
1993
1993
Thrombotic complications of BMT: association with protein C deficiency.
A decrease in levels of circulating anticoagulant protein C has been shown to occur following autologous BMT, and this deficiency… 
Highly Cited
1989
Highly Cited
1989
CONGENITAL SEVERE PROTEIN C DEFICIENCY IN ADULTS
We (Melissari et al, 1985, T.R. 29 [1985] 641) were the first to identify the occurrence of severe protein C deficiency in an… 
1986
1986
Recurrent coumarin-induced skin necrosis in a patient with an acquired functional protein C deficiency.
An elderly woman who had been receiving long-term oral anticoagulant therapy developed skin and subcutaneous fat necrosis on five… 
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