Protein C Deficiency

Known as: Hereditary Thrombophilia Due To Protein C Deficiency, Protein C Deficiencies, c protein deficiency 
An absence or deficiency in PROTEIN C which leads to impaired regulation of blood coagulation. It is associated with an increased risk of severe or… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Severe protein C deficiency (i.e. protein C activity <1 IU dL(-1)) is a rare autosomal recessive disorder that usually presents… (More)
  • figure 1
  • figure 2
  • table 1
Is this relevant?
Highly Cited
2001
Highly Cited
2001
STUDY OBJECTIVE To investigate whether protein C levels predict 30-day mortality rate, shock status, duration of ICU stay, and… (More)
  • table 1
  • table 2
  • table 3
  • figure 1
  • table 4
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Reported prevalence rates for protein C (PC) deficiency in the population at large have varied widely. The differences presumably… (More)
Is this relevant?
Highly Cited
1989
Highly Cited
1989
A family with a high incidence of venous thromboembolism was investigated. We performed medical evaluations on 184 of the 411… (More)
  • figure 1
  • table 1
  • figure 2
  • table 2
Is this relevant?
Highly Cited
1987
Highly Cited
1987
Protein C deficiency has been thought to be associated with an increased risk of venous thrombosis. To establish a normal range… (More)
Is this relevant?
1985
1985
Hereditary protein C deficiency, which is inherited as an autosomal-dominant trait, predisposes to venous thrombotic disease… (More)
Is this relevant?
Highly Cited
1984
Highly Cited
1984
We studied a family in which two infants had died with massive venous thrombosis shortly after birth. Protein C antigen was… (More)
Is this relevant?
Highly Cited
1984
Highly Cited
1984
Recent studies have demonstrated that protein C deficiency is associated with recurrent familial thrombosis. In plasma, activated… (More)
  • figure 3
  • figure 1
  • figure 2
  • figure 4
  • table I
Is this relevant?
Highly Cited
1983
Highly Cited
1983
Protein C is the zymogen of a vitamin K-dependent serine protease involved in blood coagulation. In the absence of protein C the… (More)
Is this relevant?
Highly Cited
1983
Highly Cited
1983
A coumarin-responsive chronic relapsing purpura fulminans syndrome is described in a protein-C-deficient newborn infant. Episodes… (More)
Is this relevant?