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Protease Nexins

Known as: Nexin, Protease, Nexin, Protease Associated, Protease Nexin 
Extracellular protease inhibitors that are secreted from FIBROBLASTS. They form a covalent complex with SERINE PROTEASES and can mediate their… 
National Institutes of Health

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In BloodProcess of secretionagonistsantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Protease nexin 1: a novel regulator of prostate cancer cell growth and neo-angiogenesis
Prostate adenocarcinoma (CaP) is the most frequent cancer and second leading cause of cancer death among men in the Western world… 
1999
1999
Protease nexin I expression is up‐regulated in human skeletal muscle by injury‐related factors
Protease nexin I is a 43–50 kDa glycoprotein capable of inhibiting a number of serine proteases. In cultured differentiated human… 
1995
1995
Reverse‐zymographic analysis of protease nexin‐II/amyloid β protein precursor of human carcinoma cell lines, with special reference to the grade of differentiation and metastatic phenotype
Trypsin inhibitors in serum‐free conditioned media (SFCM) of various human carcinoma cell lines were analyzed by reverse… 
1993
1993
Decreased levels of glia-derived nexin/protease nexin I in irradiated rat spinal cord in vivo.
The pathophysiology of the cellular basis of radiation induced demyelination and white matter necrosis of the Central Nervous… 
1991
1991
Establishment of a new human cancer cell line secreting protease nexin‐II/amyloid β protein precursor derived from squamous‐cell carcinoma of lung
A new cell line (LC‐1/sq) of human lung squatnous‐cell carcinoma was established from a surgically resected specimen of primary… 
1990
1990
Serpin inhibitors of urokinase and thrombin in normal rat brain and the 9L brain tumor: evidence for elevated expression of protease nexin I-like inhibitor and a novel sodium dodecyl sulfate…
Increasing attention is being paid to alterations of the hemostatic balance in tumors, in general, and brain tumors, in… 
1989
1989
A form of protease nexin I is expressed on the platelet surface during platelet activation.
A protein that has several similarities to protease nexin I, a fibroblast thrombin and urokinase inhibitor, has been detected on… 
1989
1989
A form of protease nexin I is expressed on the platelet surface during platelet activation
A protein that has several similarities to protease nexin I, a fibroblast thrombin and urokinase inhibitor, has been detected on… 
1986
1986
A simple two-step purification of protease nexin.
This paper describes a simple purification procedure for protease nexin, a serine proteinase inhibitor secreted by cultured human… 
1986
1986
Formation of protease nexin‐thrombin complexes on the platelet surface
We have recently described a platelet factor that is similar to the fibroblast thrombin inhibitor protease nexin I (PNI) [12… 
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