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Propofol

Known as: 2,6-Diisopropylphenol, Phenol, 2,6-bis(1-methylethyl)-, Propofolum 
A hypnotic alkylphenol derivative. Formulated for intravenous induction of sedation and hypnosis during anesthesia, propofol facilitates inhibitory… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
PurposeCancer-related mortality, a leading cause of death worldwide, is often the result of metastatic disease recurrence… Expand
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Highly Cited
2012
Highly Cited
2012
CONTEXT Long-term sedation with midazolam or propofol in intensive care units (ICUs) has serious adverse effects. Dexmedetomidine… Expand
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Highly Cited
2000
Highly Cited
2000
Background: Target-controlled infusion is an increasingly common type of administration for propofol. This method requires… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND The authors studied the influence of age on the pharmacodynamics of propofol, including characterization of the… Expand
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Highly Cited
1998
Highly Cited
1998
Background Unresolved issues with propofol include whether the pharmacokinetics are linear with dose, are influenced by method of… Expand
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Highly Cited
1997
Highly Cited
1997
BACKGROUND: The bispectral index (BIS), a value derived from the electroencephalograph (EEG), has been proposed as a measure of… Expand
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Highly Cited
1997
Highly Cited
1997
Background: The bispectral index (BIS), a parameter derived from the electroencephalograph (EEG), has been shown to correlate… Expand
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Highly Cited
1991
Highly Cited
1991
A computer controlled infusion device for propofol was used to induce and maintain general anaesthesia in 20 children undergoing… Expand
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Highly Cited
1988
Highly Cited
1988
The haemodynamic effects of propofol, given as a single dose of 2 mg kg-1 immediately followed by a continuous infusion of 6 mg… Expand
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Highly Cited
1988
Highly Cited
1988
The pharmacokinetic and pharmacodynamic properties of propofol were studied in 50 surgical patients. Propofol was administered as… Expand
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