Propafenone

Known as: Propafenona, Propafenone [Chemical/Ingredient], 1-(2-(2-Hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-1-propanone 
An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
AIMS Mixed treatment comparisons (MTC) were performed to assess the relative efficacy and tolerability of the main anti… (More)
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Review
2005
Review
2005
UDP-glucuronosyltransferase (UGT) enzymes catalyze the conjugation of various endogenous substances (e.g., bilirubin) and… (More)
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Highly Cited
2004
Highly Cited
2004
STUDY OBJECTIVES The relative risks and benefits of strategies of rate control vs rhythm control in patients with atrial… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND We conducted a prospective, multicenter, randomized comparison of implantable cardioverter-defibrillator (ICD) versus… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND The restoration and maintenance of sinus rhythm is a desirable goal in patients with atrial fibrillation, because the… (More)
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Highly Cited
1993
Highly Cited
1993
Because conventional antiarrhythmic therapy is often ineffective in maintaining sinus rhythm or is associated with adverse side… (More)
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1993
1993
Propafenone, a class 1c antiarrhythmic agent, is known to be a potent blocker of voltage-dependent sodium channels; however… (More)
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Highly Cited
1988
Highly Cited
1988
We calculated the wavelength of the atrial impulse in chronically instrumented conscious dogs by measuring both conduction… (More)
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Highly Cited
1987
Highly Cited
1987
The relationship between debrisoquine metabolic phenotype and the pharmacokinetics and pharmacodynamics of propafenone was… (More)
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1984
1984
Previous studies of widely different concentrations of propafenone in various species have reported that in addition to having… (More)
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