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Propafenone

Known as: Propafenona, Propafenone [Chemical/Ingredient], 1-(2-(2-Hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-1-propanone 
An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.
National Institutes of Health

Related topics

Related topics

41 relations
12 HR Propafenone Hydrochloride 225 MG Extended Release Oral CapsuleAmprenavirAtrial FibrillationBradycardia

Narrower (10)

5-hydroxypropafenoneBaxarytmonFenoprainN-depropylpropafenone

Broader (2)

Anti-Arrhythmia AgentsVoltage-Gated Sodium Channel Blockers

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2003
Review
2003
Outpatient prescribing of antiarrhythmic drugs from 1995 to 2000.
2001
2001
The influence of CYP2D6 polymorphism on the antiarrhythmic efficacy of propafenone in patients with paroxysmal atrial fibrillation during 3 months propafenone prophylactic treatment.
OBJECTIVE Propafenone (PPF) is an antiarrhythmic, Class Ic agent. Its metabolism is genetically controlled by a cytochrome P450… 
2000
2000
Taste effects of lingual application of cardiovascular medications
1999
1999
Five caffeine metabolite ratios to measure tobacco-induced CYP1A2 activity and their relationships with urinary mutagenicity and urine flow.
To choose a sensitive protocol to discriminate populations exposed and not exposed to inducers, five urinary metabolite ratios… 
Review
1998
Review
1998
Drug treatment of atrial fibrillation in the managed care era.
1997
1997
Pilot study and protocol of the Canadian Trial of Atrial Fibrillation (CTAF).
Review
1994
Review
1994
Management of atrial flutter after the Fontan procedure.
1994
1994
Quinidine‐enhanced β‐blockade during treatment with propafenone in extensive metabolizer human subjects
Propafenone, a sodium channel blocking antiarrhythmic drug with β‐blocking properties, is metabolized to non‐β‐blocking… 
Highly Cited
1982
Highly Cited
1982
Suppression of Ventricular Arrhythmias by Propafenone, a New Antiarrhythmic Agent, During Acute Myocardial Infarction in the Conscious Dog A Comparative Study with Lidocaine
The responsiveness of ventricular tachycardia (VT) to propafenone, a new antiarrhythmic agent, was evaluated in the conscious dog… 
Highly Cited
1981
Highly Cited
1981
Electrophysiological effects of propafenone studied with programmed electrical stimulation of the heart in patients with recurrent paroxysmal supraventricular tachycardia.
Propafenone is an antiarrhythmic which possesses the properties of a class I agent. Its electrophysiological effects were studied… 
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