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Propafenone

Known as: Propafenona, Propafenone [Chemical/Ingredient], 1-(2-(2-Hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-1-propanone 
An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.
National Institutes of Health

Related topics

Related topics

41 relations
12 HR Propafenone Hydrochloride 225 MG Extended Release Oral CapsuleAmprenavirAtrial FibrillationBradycardia

Narrower (10)

5-hydroxypropafenoneBaxarytmonFenoprainN-depropylpropafenone

Broader (2)

Anti-Arrhythmia AgentsVoltage-Gated Sodium Channel Blockers

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Management of atrial fibrillation in seven European countries after the publication of the 2010 ESC Guidelines on atrial fibrillation: primary results of the PREvention oF thromboemolic events…
Aims We sought to describe the management of patients with atrial fibrillation (AF) in Europe after the release of the 2010 AF… 
Review
2010
Review
2010
Meta-analysis of ablation of atrial flutter and supraventricular tachycardia.
Highly Cited
2002
Highly Cited
2002
Inhibition of the current of heterologously expressed HERG potassium channels by flecainide and comparison with quinidine, propafenone and lignocaine
The inhibition of the cardiac ‘rapid’ delayed rectifier current (IKr) and its cloned equivalent HERG mediate QT interval… 
Highly Cited
2000
Highly Cited
2000
Amiodarone to prevent recurrence of atrial fibrillation. Canadian Trial of Atrial Fibrillation Investigators.
BACKGROUND The restoration and maintenance of sinus rhythm is a desirable goal in patients with atrial fibrillation, because the… 
Highly Cited
1999
Highly Cited
1999
Pretreatment with verapamil in patients with persistent or chronic atrial fibrillation who underwent electrical cardioversion.
Highly Cited
1994
Highly Cited
1994
Implantable cardioverter defibrillator compared with antiarrhythmic drug treatment in cardiac arrest survivors (the Cardiac Arrest Study Hamburg).
Review
1992
Review
1992
Amiodarone. An overview of its pharmacological properties, and review of its therapeutic use in cardiac arrhythmias.
Amiodarone, originally developed over 20 years ago, is a potent antiarrhythmic drug with the actions of all antiarrhythmic drug… 
Highly Cited
1990
Highly Cited
1990
Therapy of refractory symptomatic atrial fibrillation and atrial flutter: a staged care approach with new antiarrhythmic drugs.
Highly Cited
1988
Highly Cited
1988
Length of Excitation Wave and Susceptibility to Reentrant Atrial Arrhythmias in Normal Conscious Dogs
We calculated the wavelength of the atrial impulse in chronically instrumented conscious dogs by measuring both conduction… 
Highly Cited
1987
Highly Cited
1987
Polymorphism of propafenone metabolism and disposition in man: clinical and pharmacokinetic consequences.
The relationship between debrisoquine metabolic phenotype and the pharmacokinetics and pharmacodynamics of propafenone was… 
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