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Pregnenolone
Known as:
Pregn-5-en-20-one, 3-hydroxy-, (3beta)-
, Pregnenolone [Chemical/Ingredient]
, 5 Pregnen 3 beta ol 20 one
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An endogenous steroid hormone synthesized from cholesterol, which can act either as a neuroactive steroid or as a prohormone for progestogens…
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National Institutes of Health
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Related topics
Related topics
33 relations
Narrower (19)
16-dehydropregnenolone
16-hydroxypregnenolone
16-pregnolone
21,21-dichloropregnenolone
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Broader (3)
Hydroxycorticosteroids
Progestins
progesterone analog
In Blood
Pregnenolone:MRat:24H:Urine:Qn
Pregnenolone:SCnc:Pt:Ser/Plas:Qn
Process of secretion
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Synthesis of 21,21-difluoro-3 beta-hydroxy-20-methylpregna-5,20-diene and 5,16,20-triene as potential inhibitors of steroid C17(20) lyase.
P. Weintraub
,
Amy K. Holland
,
+4 authors
N. Peet
Bioorganic & Medicinal Chemistry
2003
Corpus ID: 5648462
Highly Cited
2000
Highly Cited
2000
Increased neurosteroids synthesis after brain and spinal cord injury in rats
F. Michele
,
D. Lekieffre
,
A. Pasini
,
G. Bernardi
,
J. Benavides
,
E. Romeo
Neuroscience Letters
2000
Corpus ID: 2644112
1995
1995
Stimulation of progesterone secretion in dispersed cells of rat corpora lutea by antioxidants
J. Carlson
,
M. Sawada
,
D. Boone
,
Julie M. Stauffer
Steroids
1995
Corpus ID: 31350934
Highly Cited
1992
Highly Cited
1992
Progesterone blocks cholesterol translocation from lysosomes.
J. D. Butler
,
J. Blanchette-Mackie
,
+7 authors
Adele Cooney
Journal of Biological Chemistry
1992
Corpus ID: 46552279
Highly Cited
1991
Highly Cited
1991
2,3,7,8-Tetrachlorodibenzo-p-dioxin inhibits steroidogenesis in the rat testis by inhibiting the mobilization of cholesterol to cytochrome P450scc.
Robert W. Moore
,
C. Jefcoate
,
R. Peterson
Toxicology and Applied Pharmacology
1991
Corpus ID: 20070906
Highly Cited
1989
Highly Cited
1989
Steroid synthesis in rat brain cell cultures.
I. Jung-Testas
,
Z. Hu
,
E. Baulieu
,
P. Robel
Journal of Steroid Biochemistry
1989
Corpus ID: 23362479
1985
1985
The non-specific lipid transfer protein (sterol carrier protein 2) from rat and bovine liver.
A. V. Amerongen
,
Tom Teerlink
,
G.P.H. Van Heusden
,
Karel W.A. Wirtz
Chemistry and Physics of Lipids
1985
Corpus ID: 25059674
Highly Cited
1981
Highly Cited
1981
Induction of synthesis of cholesterol side chain cleavage cytochrome P-450 by adrenocorticotropin in cultured bovine adrenocortical cells.
Raymond N. DuBois
,
Evan R. Simpson
,
Robert E. Kramer
,
Michael R. Waterman
Journal of Biological Chemistry
1981
Corpus ID: 28325943
Highly Cited
1975
Highly Cited
1975
Unconjugated steroids in the human endometrium.
R. Guerrero
,
B. Landgren
,
R. Montiel
,
Z. Čekan
,
E. Diczfalusy
Contraception
1975
Corpus ID: 46531492
Review
1963
Review
1963
PRESENT STATUS OF RESEARCH ON CATABOLISM AND EXCRETION OF CHOLESTEROL.
Henry Danielsson
Advances in Lipid Research
1963
Corpus ID: 29484702
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