Pregnenolone

Known as: Pregn-5-en-20-one, 3-hydroxy-, (3beta)-, Pregnenolone [Chemical/Ingredient], 5 Pregnen 3 beta ol 20 one 
An endogenous steroid hormone synthesized from cholesterol, which can act either as a neuroactive steroid or as a prohormone for progestogens… (More)
National Institutes of Health

Papers overview

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2011
2011
In humans, the precursor to all steroid hormones, pregnenolone, is synthesized from cholesterol by an enzyme complex comprising… (More)
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Highly Cited
2002
Highly Cited
2002
The multidrug resistance-associated protein 2 (MRP2, ABCC2), mediates the efflux of several conjugated compounds across the… (More)
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Highly Cited
2002
Highly Cited
2002
1: The pharmacology of the stable cell line expressing human alpha(4)beta(3)delta GABA(A) receptor was investigated using whole… (More)
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1998
Highly Cited
1998
Steroid hormones exert profound effects on differentiation, development, and homeostasis in higher eukaryotes through… (More)
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1998
1998
The first two steps of the steroidogenic pathway were reproduced in Saccharomyces cerevisiae. Engineering of sterol biosynthesis… (More)
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Highly Cited
1995
Highly Cited
1995
screen of the microscope. Between 150 to 300 nerve fibers were analyzed per cross section. 13. C. F. Eldridge, M. Bartlett, R. P… (More)
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1995
1995
The present study was carried out to determine steroid biosynthesis from cholesterol in the brain of adult male Japanese quails… (More)
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1994
1994
Recently several steroid compounds have been discovered to act as neuromodulators in diverse central nervous system (CNS… (More)
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Highly Cited
1989
Highly Cited
1989
Cells dissociated from newborn rat forebrains were established in long term primary cultures. The cultures were made up almost… (More)
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1987
Highly Cited
1987
Oligodendrocyte mitochondria from 21-day-old Sprague-Dawley male rats were incubated with 100 nM [3H]cholesterol. It yielded [3H… (More)
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