Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Pregnenolone

Known as: Pregn-5-en-20-one, 3-hydroxy-, (3beta)-, Pregnenolone [Chemical/Ingredient], 5 Pregnen 3 beta ol 20 one 
An endogenous steroid hormone synthesized from cholesterol, which can act either as a neuroactive steroid or as a prohormone for progestogens… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Steroidogenesis entails processes by which cholesterol is converted to biologically active steroid hormones. Whereas most… Expand
Highly Cited
2011
Highly Cited
2011
In humans, the precursor to all steroid hormones, pregnenolone, is synthesized from cholesterol by an enzyme complex comprising… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Highly Cited
2002
Highly Cited
2002
The multidrug resistance-associated protein 2 (MRP2, ABCC2), mediates the efflux of several conjugated compounds across the… Expand
  • figure 1
  • figure 2
  • figure 4
  • figure 5
  • figure 6
Review
2001
Review
2001
Aging is a general process of functional decline which involves in particular a decline of cognitive abilities. However, the… Expand
Highly Cited
1998
Highly Cited
1998
Steroid hormones exert profound effects on differentiation, development, and homeostasis in higher eukaryotes through… Expand
  • figure 4
  • figure 3
  • figure 5
  • figure 6
Review
1997
Review
1997
Steroidogenesis begins with the metabolism of cholesterol to pregnenolone by the inner mitochondrial membrane cytochrome P450… Expand
Highly Cited
1995
Highly Cited
1995
screen of the microscope. Between 150 to 300 nerve fibers were analyzed per cross section. 13. C. F. Eldridge, M. Bartlett, R. P… Expand
  • figure 1
  • figure 2
  • figure 3
Highly Cited
1989
Highly Cited
1989
Delivery of cholesterol to inner mitochondrial membranes is rate-limiting for steroidogenesis in the zona fasciculata of adrenal… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 4
Highly Cited
1987
Highly Cited
1987
Oligodendrocyte mitochondria from 21-day-old Sprague-Dawley male rats were incubated with 100 nM [3H]cholesterol. It yielded [3H… Expand
Highly Cited
1983
Highly Cited
1983
Ketoconazole has recently been shown to interfere with steroidogenesis in patients and rat in vitro systems. In this study we… Expand
  • table II
  • table I
  • figure 1
  • figure 2
  • figure 3