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Polyoma Virus Middle T Staining Method

Known as: PYMT Staining Method 
Polyoma virus encodes three proteins, the large T (PyLT), middle T (PymT), and small T (Pyst) antigens, that bind p53 and thus block the function of… Expand
National Institutes of Health

Papers overview

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2019
2019
Abstract 2649: A novel approach to fate-map hypoxic cells during tumor progression uncovers metastatic potency of post-hypoxic cells
  • Inês Godet, Yu Jung Shin, +5 authors Daniele M. Gilkes
  • 2019
    • Corpus ID: 219266395
Hypoxia occurs in 90% of solid tumors due to inefficient vasculature and has been demonstrated to promote a more aggressive… Expand
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2017
2017
A Versatile Tumor Gene Deletion System Reveals a Crucial Role for FGFR1 in Breast Cancer Metastasis
RCAS avian viruses have been used to deliver oncogene expression and induce tumors in transgenic mice expressing the virus… Expand
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2017
2017
Bone-Seeking Matrix Metalloproteinase-2 Inhibitors Prevent Bone Metastatic Breast Cancer Growth.
Bone metastasis is common during breast cancer progression. Matrix metalloproteinase-2 (MMP-2) is significantly associated with… Expand
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2017
2017
PyMT-Maclow: A novel, inducible, murine model for determining the role of CD68 positive cells in breast tumor development
CD68+ tumor-associated macrophages (TAMs) are pro-tumorigenic, pro-angiogenic and are associated with decreased survival rates in… Expand
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Review
2015
Review
2015
The Role of Chemokine Receptors CCR6 and CCR7 in the Initiation and Progression of Breast Cancer
Cancer stem cells are believed to be a subset of heterogeneous tumour cells responsible for tumour initiation, growth, local… Expand
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2013
2013
Immunological effects of chemotherapy in spontaneous breast cancers
In 2012, the research group lead by Karin de Visser at the Netherlands Cancer Institute reported that chemotherapeutic regimens… Expand
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2013
2013
Bisected, complex N-glycans and galectins in mouse mammary tumor progression and human breast cancer.
Bisected, complex N-glycans on glycoproteins are generated by the glycosyltransferase MGAT3 and cause reduced cell surface… Expand
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Review
2011
Review
2011
Hyaluronan metabolism in remodeling extracellular matrix: probes for imaging and therapy of breast cancer.
Clinical and experimental evidence increasingly support the concept of cancer as a disease that emulates a component of wound… Expand
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Highly Cited
2006
Highly Cited
2006
Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors
BackgroundAlthough numerous mouse models of breast carcinomas have been developed, we do not know the extent to which any… Expand
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Review
2004
Review
2004
ReviewSpecificity in Signal Transduction : From Phosphotyrosine-SH 2 Domain Interactions to Complex Cellular Systems
cal way in which a single polypeptide could exert such Canada a pervasive influence on the cell (Levinson et al., 1978; Collett… Expand
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