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Polymerase Chain Reaction

Known as: Reaction, Polymerase Chain, polymerase chain reaction (PCR), PCR 
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short… 
National Institutes of Health

Related topics

Related topics

14 relations

Narrower (5)

Anchored PCRInverse PCRNested Polymerase Chain ReactionRandom Amplified Polymorphic DNA Technique
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Clinical Data Interchange Standards Consortium TerminologyCloning, MolecularLigase Chain ReactionPolymerase chain reaction analysis
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Broader (1)

genetic technology

Papers overview

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Highly Cited
1997
Highly Cited
1997
Product differentiation by analysis of DNA melting curves during the polymerase chain reaction.
A microvolume fluorometer integrated with a thermal cycler was used to acquire DNA melting curves during polymerase chain… 
Highly Cited
1995
Highly Cited
1995
AFLP: a new technique for DNA fingerprinting.
A novel DNA fingerprinting technique called AFLP is described. The AFLP technique is based on the selective PCR amplification of… 
Highly Cited
1993
Highly Cited
1993
Profiling of complex microbial populations by denaturing gradient gel electrophoresis analysis of polymerase chain reaction-amplified genes coding for 16S rRNA
We describe a new molecular approach to analyzing the genetic diversity of complex microbial populations. This technique is based… 
Highly Cited
1992
Highly Cited
1992
Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction.
Effective methods are needed to identify and isolate those genes that are differentially expressed in various cells or under… 
Highly Cited
1991
Highly Cited
1991
Detection of specific polymerase chain reaction product by utilizing the 5'----3' exonuclease activity of Thermus aquaticus DNA polymerase.
The 5'----3' exonuclease activity of the thermostable enzyme Thermus aquaticus DNA polymerase may be employed in a polymerase… 
Highly Cited
1989
Highly Cited
1989
Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction.
  • J. Weber, P. May
  • American journal of human genetics
  • 1989
  • Corpus ID: 45216530
Interspersed DNA elements of the form (dC-dA)n.(dG-dT)n constitute one of the most abundant human repetitive DNA families. We… 
Highly Cited
1989
Highly Cited
1989
Site-directed mutagenesis by overlap extension using the polymerase chain reaction.
Highly Cited
1988
Highly Cited
1988
Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase.
A thermostable DNA polymerase was used in an in vitro DNA amplification procedure, the polymerase chain reaction. The enzyme… 
Highly Cited
1988
Highly Cited
1988
Genetic applications of an inverse polymerase chain reaction.
A method is presented for the rapid in vitro amplification of DNA sequences that flank a region of known sequence. The method… 
Highly Cited
1986
Highly Cited
1986
Specific enzymatic amplification of DNA in vitro: the polymerase chain reaction.
The discovery of specific restriction endonucleases (Smith and Wilcox 1970) made possible the isolation of discrete molecular… 
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