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Polymerase Chain Reaction
Known as:
Reaction, Polymerase Chain
, polymerase chain reaction (PCR)
, PCR
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In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short…
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National Institutes of Health
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Related topics
Related topics
14 relations
Narrower (5)
Anchored PCR
Inverse PCR
Nested Polymerase Chain Reaction
Random Amplified Polymorphic DNA Technique
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Clinical Data Interchange Standards Consortium Terminology
Cloning, Molecular
Ligase Chain Reaction
Polymerase chain reaction analysis
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Broader (1)
genetic technology
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Polymerase chain reaction primers miss half of rRNA microbial diversity
Sunhee Hong
,
J. Bunge
,
C. Leslin
,
Sunok Jeon
,
S. Epstein
The ISME Journal
2009
Corpus ID: 5551264
The rRNA approach is the principal tool to study microbial diversity, but it has important biases. These include polymerase chain…
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Highly Cited
2003
Highly Cited
2003
A short history of the polymerase chain reaction.
J. Bartlett
,
D. Stirling
Methods in molecular biology
2003
Corpus ID: 39910976
A Short History of the Polymerase Chain Reaction. In the 1950s, the discovery of PCR is the subject of claim and counterclaim…
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Highly Cited
2002
Highly Cited
2002
Quantitative assessment of hematopoietic chimerism after bone marrow transplantation by real-time quantitative polymerase chain reaction.
M. Alizadeh
,
M. Bernard
,
+9 authors
E. Quelvennec
Blood
2002
Corpus ID: 248569
We have developed a real-time quantitative polymerase chain reaction (PCR) assay using TaqMan technology (Applied Biosystems…
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Highly Cited
1996
Highly Cited
1996
The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds
S. Tavtigian
,
J. Simard
,
+49 authors
D. Goldgar
Nature Genetics
1996
Corpus ID: 8774390
Breast carcinoma is the most common malignancy among women in developed countries. Because family history remains the strongest…
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Highly Cited
1993
Highly Cited
1993
Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits.
T. Ishii
,
K. Moriyoshi
,
+8 authors
Shigetada Nakanishie
Journal of Biological Chemistry
1993
Corpus ID: 23068410
Highly Cited
1993
Highly Cited
1993
The sensitivity of single-strand conformation polymorphism analysis for the detection of single base substitutions.
V. Sheffield
,
J. Beck
,
A. Kwitek
,
Dirk W. Sandstrom
,
E. Stone
Genomics
1993
Corpus ID: 22573912
Single-strand conformation polymorphism (SSCP) analysis has proven to be a simple and effective technique for the detection of…
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Highly Cited
1992
Highly Cited
1992
Use of repetitive (repetitive extragenic palindromic and enterobacterial repetitive intergeneric consensus) sequences and the polymerase chain reaction to fingerprint the genomes of Rhizobium…
F. J. Bruijn
1992
Corpus ID: 82752145
Thedistribution ofdispersed repetitive DNA (repetitive extragenic palindromic [REP]andenterobacterial repetitive intergenic…
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Review
1991
Review
1991
DNA polymerase fidelity and the polymerase chain reaction.
K. Eckert
,
T. Kunkel
PCR methods and applications
1991
Corpus ID: 15453159
High-fidelity DNA synthesis conditions are those that exploit the inherent ability of polymerases to discriminate against errors…
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Highly Cited
1989
Highly Cited
1989
Cloning immunoglobulin variable domains for expression by the polymerase chain reaction.
R. Orlandi
,
D. Güssow
,
Peter T. Jones
,
G. Winter
Proceedings of the National Academy of Sciences…
1989
Corpus ID: 34327764
We have designed a set of oligonucleotide primers to amplify the cDNA of mouse immunoglobulin heavy and light chain variable…
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Highly Cited
1989
Highly Cited
1989
Alu polymerase chain reaction: a method for rapid isolation of human-specific sequences from complex DNA sources.
David L. Nelson
,
Susan A. LEDBETrERt
,
+5 authors
C. Caskey
Proceedings of the National Academy of Sciences…
1989
Corpus ID: 32138007
Current efforts to map the human genome are focused on individual chromosomes or smaller regions and frequently rely on the use…
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