Ligase Chain Reaction

Known as: Reactions, Ligase Chain, Reaction, Ligase Chain, Ligase Chain Reactions 
A DNA amplification technique based upon the ligation of OLIGONUCLEOTIDE PROBES. The probes are designed to exactly match two adjacent sequences of a… (More)
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Assembly of DNA parts into DNA constructs is a foundational technology in the emerging field of synthetic biology. An efficient… (More)
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Highly Cited
2007
Highly Cited
2007
The predictive value of KRAS mutation in metastatic colorectal cancer (MCRC) patients treated with cetuximab plus chemotherapy… (More)
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Highly Cited
1998
Highly Cited
1998
The presence of endogenous amplification inhibitors in urine may produce false-negative results for the detection of Chlamydia… (More)
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1998
1998
The accuracy of pooling urine samples for the detection of genital Chlamydia trachomatis infection by ligase chain reaction (LCR… (More)
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1998
1998
Sputum specimens received for the diagnosis of tuberculosis or other mycobacterial infections were tested by a ligase chain… (More)
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Highly Cited
1995
Highly Cited
1995
Genitourinary infection with Chlamydia trachomatis is a common and potentially serious sexually transmitted disease. Diagnosis of… (More)
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1995
1995
DNA amplification systems are powerful technologies with the potential to impact a wide range of diagnostic applications. In this… (More)
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Highly Cited
1994
Highly Cited
1994
From April to September 1993, 305 men and 447 women in Hamilton, Canada, consented to the collection of a urethral or cervical… (More)
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Highly Cited
1994
Highly Cited
1994
We performed a multicenter evaluation of ligase chain reaction (LCR) in the diagnosis of Chlamydia trachomatis infection of the… (More)
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1993
1993
Amplification of Chlamydia trachomatis DNA by polymerase chain reaction was compared with amplification by ligase chain reaction… (More)
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