Skip to search formSkip to main contentSkip to account menu

Ligase Chain Reaction

Known as: Reactions, Ligase Chain, Reaction, Ligase Chain, Ligase Chain Reactions 
A DNA amplification technique based upon the ligation of OLIGONUCLEOTIDE PROBES. The probes are designed to exactly match two adjacent sequences of a… 
National Institutes of Health

Related topics

Related topics

2 relations
Polymerase Chain Reactionstandards characteristics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Simultaneous detection of recombinant DNA segments introduced into genetically modified crops with multiplex ligase chain reaction coupled with multiplex polymerase chain reaction.
We developed a multiplex polymerase chain reaction (PCR)-multiplex ligase chain reaction (LCR) (MPCR-MLCR) technique as a novel… 
2004
2004
Real-Time Gap Ligase Chain Reaction
Purpose: We have developed a real-time semiquantitative gap ligase chain reaction for detecting p53 point mutations at low level… 
2003
2003
Detection of HLA polymorphisms by ligase detection reaction and a universal array format: a pilot study for low resolution genotyping.
2001
2001
Optimised sample DNA preparation for detection ofChlamydia trachomatis in synovial tissue by polymerase chain reaction and ligase chain reaction
OBJECTIVE Molecular biology techniques such as polymerase chain reaction (PCR) and ligase chain reaction (LCR) are routinely used… 
1999
1999
Needle-in-a-haystack detection and identification of base substitution mutations in human tissues.
1998
1998
Preparation and validation of PCR-generated positive controls for diagnostic dot blotting.
Allele-specific oligonucleotides (ASOs) are small, single-stranded nucleotide polymers (∼18–20 bases in length) of diagnostic… 
1997
1997
False-negative results of a ligase chain reaction assay to detectChlamydia trachomatis due to inhibitors in urine
The aim of this study was to assess the presence of inhibitors in urine specimens causing false-negative results in a… 
1996
1996
Analysis of ligase chain reaction products via matrix-assisted laser desorption/ionization time-of-flight-mass spectrometry.
A rapid and accurate detection of ligation products generated in ligase chain reactions (LCR) by using matrix-assisted laser… 
1996
1996
Urine as a Diagnostic Specimen for the Detection of Chlamydia trachomatis in Malaysia by Ligase Chain Reaction
Background and Objectives: Noninvasive urine screening for Chlamydia trachomatis infections offers a valuable public health tool… 
Review
1993
Review
1993
The ligase chain reaction in DNA-based diagnosis.
Clinical specimens containing a suspected pathogen often have too little of the pathogen's DNA to be detected directly. It is… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)