FAQ

Poly [ADP-Rbose] Polymerase 1 p85

Known as: ADPRT 1 p85, Poly(ADP Ribose) Polymerase p85, PARP1 p85 
Poly [ADP-ribose] polymerase 1 p85 (800 aa, ~89 kDa) is encoded by the human PARP1 gene. This protein is released from the full length poly [ADP… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1981-2017
0246819812017

Related topics

Related topics

3 relations
DNA RepairDNA Repair GenePARP1 gene

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Poly [ADP-Rbose] Polymerase 1 p85
DNA Repair
PARP1 gene
DNA Repair Gene

Papers overview

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2009
2009
P-glycoprotein interfering agents potentiate ivermectin susceptibility in ivermectin sensitive and resistant isolates of Teladorsagia circumcincta and Haemonchus contortus.
P-glycoprotein (P-gp) homologues, belonging to the ATP Binding Cassette (ABC) transporter family, are thought to play an… (More)
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2007
2007
Improvement of the oral drug absorption of topotecan through the inhibition of intestinal xenobiotic efflux transporter, breast cancer resistance protein, by excipients.
Recently, breast cancer resistance protein (BCRP/ABCG2) has been shown to limit the oral absorption of its substrates in the… (More)
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2005
2005
Promoter- and strain-selective enhancement of gene expression in a mouse skeletal muscle by a polymer excipient Pluronic P85.
Amphiphilic triblock copolymers of ethylene oxide and propylene oxide (Pluronic) significantly enhanced expression of plasmid DNA… (More)
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2004
2004
Effect of Pluronic P85 on ATPase Activity of Drug Efflux Transporters
Pluronic block copolymers are potent sensitizers of multidrug resistant (MDR) cancer cells. The sensitization effect by Pluronics… (More)
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2004
2004
Basic fibroblast growth factor stimulates activation of Rac1 through a p85 betaPIX phosphorylation-dependent pathway.
In a previous study (Shin, E. Y., Shin, K. S., Lee, C. S., Woo, K. N., Quan, S. H., Soung, N. K., Kim, Y. G., Cha, C. I., Kim, S… (More)
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2004
2004
Insulin induces SOCS-6 expression and its binding to the p85 monomer of phosphoinositide 3-kinase, resulting in improvement in glucose metabolism.
The suppressors of cytokine signaling (SOCS) family is thought to act largely as a negative regulator of signaling by cytokines… (More)
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2003
2003
Sensitization of Cells Overexpressing Multidrug-Resistant Proteins by Pluronic P85
Purpose. This study evaluated the chemosensitizing effects of Pluronic P85 (P85) on cells expressing multidrug resistance… (More)
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Highly Cited
2001
Highly Cited
2001
Mechanism of sensitization of MDR cancer cells by Pluronic block copolymers: Selective energy depletion
This paper, for the first time, demonstrates that exposure of cells to the poly(ethylene oxide)-poly(propylene oxide) block… (More)
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1999
1999
Pluronic P85 Increases Permeability of a Broad Spectrum of Drugs in Polarized BBMEC and Caco-2 Cell Monolayers
Purpose. Previous studies demonstrated that inhibition of P glycoprotein (P-gp) by Pluronic P85 (P85) block copolymer increases… (More)
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1996
1996
Hypersensitization of multidrug resistant human ovarian carcinoma cells by pluronic P85 block copolymer.
The chemosensitizing effect of Pluronic P85 block copolymer were studied using two human ovarian carcinoma sublines: the… (More)
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