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Plasminogen Activator Inhibitor 2

Known as: Serpin B2, PAI-2, Type 2 Plasminogen Activator Inhibitor 
Member of the serpin family of proteins. It inhibits both the tissue-type and urokinase-type plasminogen activators.
National Institutes of Health

Related topics

Related topics

18 relations
In BloodPlasminogen Activator Inhibitor 1Plasminogen activator inhibitor 2 Ag:ACnc:Pt:PPP:Qn:IAProcess of secretion

Narrower (1)

Plasminogen Activator Inhibitor 2, human

Broader (2)

Plasminogen InactivatorsSerine Proteinase Inhibitors

Papers overview

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Highly Cited
2004
Highly Cited
2004
Short-term cytotoxic effects and long-term instability of RNAi delivered using lentiviral vectors
BackgroundRNA interference (RNAi) can potently reduce target gene expression in mammalian cells and is in wide use for loss-of… 
Highly Cited
1999
Highly Cited
1999
Roles of Pseudomonas aeruginosa las andrhl Quorum-Sensing Systems in Control of Twitching Motility
ABSTRACT Pseudomonas aeruginosa is a ubiquitous environmental bacterium and an important human pathogen. The production of… 
Review
1997
Review
1997
Structure, Function and Expression on Blood and Bone Marrow Cells of the Urokinase‐Type Plasminogen Activator Receptor, uPAR
Several important functions have been assigned to the receptor for urokinase‐type plasminogen activator, uPAR. As implied by the… 
Review
1995
Review
1995
Plasminogen activators and plasminogen activator inhibitors: biochemical aspects.
Although this chapter does not represent a historical review, it will be clear how the biochemistry of t-PA, u-PA, PAI-1 and PAI… 
Highly Cited
1995
Highly Cited
1995
Increased procoagulant and antifibrinolytic activities in the lungs with idiopathic pulmonary fibrosis.
Highly Cited
1995
Highly Cited
1995
Urokinase plasminogen activator and urokinase plasminogen activator receptor in breast cancer
Urokinase plasminogen activator (uPA) is a serine protease involved in cancer invasion and metastasis. uPA mediates its action… 
Highly Cited
1994
Highly Cited
1994
Prognostic relevance of plasminogen activators and their inhibitors in colorectal cancer.
Human colorectal carcinogenesis has been shown previously to be associated with impressive changes in the tissue levels of… 
Highly Cited
1990
Highly Cited
1990
Inhibition of receptor-bound urokinase by plasminogen-activator inhibitors.
Review
1988
Review
1988
Plasminogen activator inhibitors--a review.
Plasminogen activator inhibitors (PAIs) are important modulators of the activity of plasminogen activators (PAs). Several… 
Highly Cited
1988
Highly Cited
1988
Plasminogen Activator Inhibitor 1 and Plasminogen Activator Inhibitor 2 in Various Disease States
Summary The association of increased PA-inhibitor (PAI) activity and of PAI-1 and PAI-2 antigen levels with different… 
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