Plasminogen Activator Inhibitor 2

Known as: Serpin B2, PAI-2, Type 2 Plasminogen Activator Inhibitor 
Member of the serpin family of proteins. It inhibits both the tissue-type and urokinase-type plasminogen activators.
National Institutes of Health

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In BloodPlasminogen Activator Inhibitor 1Plasminogen activator inhibitor 2 Ag:ACnc:Pt:PPP:Qn:IAProcess of secretion
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Narrower (1)

Plasminogen Activator Inhibitor 2, human

Broader (2)

Plasminogen InactivatorsSerine Proteinase Inhibitors

Papers overview

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Review
2009
Review
2009
The urokinase plasminogen activator system: a target for anti-cancer therapy.
The urokinase plasminogen activator (uPA) system (uPAS) consists of the uPA, its cognate receptor (uPAR) and two specific… (More)
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Review
2004
Review
2004
Urokinase-type plasminogen activator (uPA) and its inhibitor PAI-I: novel tumor-derived factors with a high prognostic and predictive impact in breast cancer.
Urokinase-type plasminogen activator (uPA) and its inhibitor, PAI-I, play a key role in tumor invasion and metastasis. They were… (More)
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Highly Cited
2000
Highly Cited
2000
The urokinase system of plasminogen activation and prognosis in 2780 breast cancer patients.
The antigen levels of components of the urokinase-type plasminogen activator (uPA) system of plasminogen activation are… (More)
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Highly Cited
1999
Highly Cited
1999
Quorum sensing in Pseudomonas aeruginosa controls expression of catalase and superoxide dismutase genes and mediates biofilm susceptibility to hydrogen peroxide.
Quorum sensing (QS) governs the production of virulence factors and the architecture and sodium dodecyl sulphate (SDS) resistance… (More)
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Highly Cited
1997
Highly Cited
1997
Regulation of las and rhl quorum sensing in Pseudomonas aeruginosa.
The production of several virulence factors by Pseudomonas aeruginosa is controlled according to cell density through two quorum… (More)
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Review
1997
Review
1997
Clinical impact of the plasminogen activation system in tumor invasion and metastasis: prognostic relevance and target for therapy.
Extravasation and intravasation of solid malignant tumors is controlled by attachment of tumor cells to components of the… (More)
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1995
1995
Plasminogen activator inhibitor-2: prognostic relevance in 1012 patients with primary breast cancer.
The antigen levels of urokinase-type plasminogen activator (uPA) and its inhibitor plasminogen activator inhibitor (PAI) 1, as… (More)
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1993
1993
Plasminogen activator inhibitor 2 reduces peritoneal fibrinolytic activity in inflammation.
Fibrinolysis in peritoneal tissue may play a role in the development of intra-abdominal adhesions. The plasminogen-activating… (More)
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Highly Cited
1990
Highly Cited
1990
Plasminogen activator inhibitor 1 and 2, alpha-2-antiplasmin, plasminogen, and endotoxin levels in systemic meningococcal disease.
We have studied the activation state of the fibrinolytic system in 39 patients with systemic meningococcal disease (SMD… (More)
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1988
1988
Plasminogen activator inhibitor 1 and plasminogen activator inhibitor 2 in various disease states.
The association of increased PA-inhibitor (PAI) activity and of PAI-1 and PAI-2 antigen levels with different pathological… (More)
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