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Plasminogen Activator Inhibitor 2

Known as: Serpin B2, PAI-2, Type 2 Plasminogen Activator Inhibitor 
Member of the serpin family of proteins. It inhibits both the tissue-type and urokinase-type plasminogen activators.
National Institutes of Health

Related topics

Related topics

18 relations
In BloodPlasminogen Activator Inhibitor 1Plasminogen activator inhibitor 2 Ag:ACnc:Pt:PPP:Qn:IAProcess of secretion
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Narrower (1)

Plasminogen Activator Inhibitor 2, human

Broader (2)

Plasminogen InactivatorsSerine Proteinase Inhibitors

Papers overview

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Review
2009
Review
2009
The urokinase plasminogen activator system: a target for anti-cancer therapy.
The urokinase plasminogen activator (uPA) system (uPAS) consists of the uPA, its cognate receptor (uPAR) and two specific… Expand
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Highly Cited
2000
Highly Cited
2000
The urokinase system of plasminogen activation and prognosis in 2780 breast cancer patients.
The antigen levels of components of the urokinase-type plasminogen activator (uPA) system of plasminogen activation are… Expand
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Highly Cited
2000
Highly Cited
2000
Binding of Factor VIIa to Tissue Factor on Keratinocytes Induces Gene Expression*
Binding of the zymogen serine protease Factor VII (FVII) to its cellular cofactor tissue factor (TF) triggers blood coagulation… Expand
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Highly Cited
1999
Highly Cited
1999
Effect of antioxidants on the occurrence of pre-eclampsia in women at increased risk: a randomised trial
BACKGROUND Oxidative stress has been implicated in the pathophysiology of pre-eclampsia. This randomised controlled trial… Expand
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Highly Cited
1999
Highly Cited
1999
Quorum sensing in Pseudomonas aeruginosa controls expression of catalase and superoxide dismutase genes and mediates biofilm susceptibility to hydrogen peroxide.
Quorum sensing (QS) governs the production of virulence factors and the architecture and sodium dodecyl sulphate (SDS) resistance… Expand
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Highly Cited
1997
Highly Cited
1997
Roles of Pseudomonas aeruginosa las and rhl quorum-sensing systems in control of elastase and rhamnolipid biosynthesis genes.
Two quorum-sensing systems (las and rhl) regulate virulence gene expression in Pseudomonas aeruginosa. The las system consists of… Expand
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Highly Cited
1997
Highly Cited
1997
Regulation of las and rhl quorum sensing in Pseudomonas aeruginosa.
The production of several virulence factors by Pseudomonas aeruginosa is controlled according to cell density through two quorum… Expand
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Review
1997
Review
1997
Clinical impact of the plasminogen activation system in tumor invasion and metastasis: prognostic relevance and target for therapy.
Extravasation and intravasation of solid malignant tumors is controlled by attachment of tumor cells to components of the… Expand
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Highly Cited
1994
Highly Cited
1994
Prognostic relevance of plasminogen activators and their inhibitors in colorectal cancer.
Human colorectal carcinogenesis has been shown previously to be associated with impressive changes in the tissue levels of… Expand
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Highly Cited
1993
Highly Cited
1993
High levels of urokinase-type plasminogen activator and its inhibitor PAI-1 in cytosolic extracts of breast carcinomas are associated with poor prognosis.
The urokinase pathway of plasminogen activation is supposed to be involved in proteolytic degradation of the extracellular matrix… Expand
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