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Plasminogen Activator Inhibitor 1

Known as: pai 1, Plasminogen Activator Inhibitor 1 [Chemical/Ingredient], PAI-1 
A member of the serpin family of proteins. It inhibits both the tissue-type and urokinase-type plasminogen activators.
National Institutes of Health

Papers overview

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Highly Cited
1994
Highly Cited
1994
We have studied the prognostic value of urokinase-type plasminogen activator (uPA), uPA receptor (uPAR), and type 1 plasminogen… Expand
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Highly Cited
1993
Highly Cited
1993
The urokinase pathway of plasminogen activation is supposed to be involved in proteolytic degradation of the extracellular matrix… Expand
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Highly Cited
1992
Highly Cited
1992
Decreased fibrinolytic capacity has been suggested to accelerate the process of arterial atherogenesis by facilitating thrombosis… Expand
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Highly Cited
1991
Highly Cited
1991
The regulation of type 1 plasminogen activator inhibitor (PAI-1) gene expression was studied in vivo employing a murine model… Expand
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Highly Cited
1991
Highly Cited
1991
The interaction between type 1 plasminogen activator inhibitor (PAI-1) and fragments of vitronectin (Vn) was investigated. The… Expand
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Highly Cited
1991
Highly Cited
1991
Regulation of the human type 1 plasminogen activator inhibitor (PAI-1) promoter by transforming growth factor-beta (TGF beta) was… Expand
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Highly Cited
1989
Highly Cited
1989
We evaluated an elderly patient with a lifelong history of severe bleeding after surgery or trauma and with evidence of… Expand
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Highly Cited
1989
Highly Cited
1989
Human HT-1080 fibrosarcoma cells produce urokinase-type plasminogen activator (u-PA) and type 1 plasminogen activator inhibitor… Expand
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Highly Cited
1989
Highly Cited
1989
Cultured bovine aortic endothelial cells (BAEs) synthesize and secrete type 1 plasminogen activator inhibitor (PAI-1), an Mr 50… Expand
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Highly Cited
1988
Highly Cited
1988
Regulation of the fibrinolytic system of cultured human umbilical vein endothelial cells (HUVECs) by recombinant interleukin 1… Expand
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