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Expression of plasminogen activator inhibitor‐1, urokinase receptor and laminin γ‐2 chain is an early coordinated event in incipient oral squamous cell carcinoma
Cancer cell invasion is facilitated by extracellular matrix degrading proteases such as plasmin. We have studied the expression of plasminogen activator inhibitor‐1 (PAI‐1) and urokinase receptorExpand
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Migration and invasion of oral squamous carcinoma cells is promoted by WNT5A, a regulator of cancer progression.
BACKGROUND Oral squamous cell carcinoma (OSCC) constitutes 90% of all cancers in the oral cavity, and the prognosis for patients diagnosed with OSCC is still poor. The identification of novelExpand
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Higher expression of WNT5A protein in oral squamous cell carcinoma compared with dysplasia and oral mucosa with a normal appearance
WNT5A is a secreted signaling protein that promotes migration and invasion of oral squamous cell carcinoma (OSCC) cells through activation of non‐canonical WNT signaling. Here, we examined expressionExpand
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Localization of plasminogen activators and plasminogen-activator inhibitors in human gingival tissues demonstrated by immunohistochemistry and in situ hybridization.
The plasminogen-activating system plays an important part in tissue proteolysis in physiological as well as pathological processes. Plasminogen activators u-PA (urokinase) and t-PA (tissue) as wellExpand
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The localization of the relaxed form of plasminogen activator inhibitor type 2 in human gingival tissues
Abstract. The plasminogen activating system is important in extracellular proteolysis. Plasmin degrades tissues and activates proteases. Plasminogen activators (tissue type; t-PA and urokinase type;Expand
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Increasing expression of tissue plasminogen activator and plasminogen activator inhibitor type 2 in dog gingival tissues with progressive inflammation.
Urokinase and tissue-type plasminogen activators (u--PA and t--PA) are serine proteases that convert plasminogen into plasmin, which degrades matrix proteins and activates metalloproteinases. The PAsExpand
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Relationship between fibrinolytic activity and gingival inflammatory reaction in young individuals.
The fibrinolytic system (the plasminogen activating system) is involved in several physiological and pathological processes. Through the transformation of plasminogen to the aggressive broad spectrumExpand
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Neuron navigator 3 alterations in nervous system tumors associate with tumor malignancy grade and prognosis
Copy number changes or reduced expression of the Neuron navigator 3 (NAV3) gene occurs in neuroblastomas and malignancies of epithelial or lymphoid origin. To elucidate whether NAV3 has a role in theExpand
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Description of the plasminogen activating system in canine gingival crevicular fluid
Abstract Summary Objective: Human gingival crevicular fluid (GCF) contains fibrinolytic activity, which has been suggested to be of significance for the etiology of periodontal diseases. We haveExpand
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Osseointegration of Titanium Implants in Onlay of Cerament™, a New Ceramic Bone Substitute
The purpose was to investigate whether a new biphasic and injectable ceramic bone substitute Cerament™ that rapidly remodels to bone, may contribute to the retention of titanium implant screws duringExpand
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