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Plasminogen Activator Inhibitor 2, human
Known as:
Monocyte Arg-Serpin
, SERPINB2
, Serine or Cysteine Proteinase Inhibitor Clade B Member 2
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Plasminogen activator inhibitor 2 (415 aa, ~47 kDa) is encoded by the human SERPINB2 gene. This protein plays a role in the modulation of both…
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National Institutes of Health
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Related topics
Related topics
7 relations
Genes, Regulator
Regulation of Proteolysis
SERPINB2 gene
SERPINB2 wt Allele
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Broader (2)
Plasminogen Activator Inhibitor 2
Plasminogen Inactivators
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Down-regulation of SerpinB2 is associated with gefitinib resistance in non-small cell lung cancer and enhances invadopodia-like structure protrusions
S. Y. Bae
,
H. Park
,
Ji-Young Hong
,
Hye-Jung Lee
,
S. Lee
Scientific Reports
2016
Corpus ID: 14137178
The failure of targeted therapy due to the resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs…
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2008
2008
Effects of platelet-derived growth factor isoforms on plasminogen activation by periodontal ligament and gingival fibroblasts.
H. Agis
,
M. Bauer
,
G. Knebl
,
G. Watzek
,
Reinhard Gruber
Journal of Periodontal Research
2008
Corpus ID: 25804231
BACKGROUND AND OBJECTIVE Platelet-derived growth factor isoforms and components of the plasminogen activator system are expressed…
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2001
2001
Interaction between the P14 Residue and Strand 2 of β-Sheet B Is Critical for Reactive Center Loop Insertion in Plasminogen Activator Inhibitor-2*
D. Saunders
,
L. Jankova
,
+4 authors
M. Baker
Journal of Biological Chemistry
2001
Corpus ID: 11534490
The molecular interactions driving reactive center loop (RCL) insertion are of considerable interest in gaining a better…
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1998
1998
Immunological Detection of Conformational Neoepitopes Associated with the Serpin Activity of Plasminogen Activator Inhibitor Type-2*
D. Saunders
,
Kathy M. L. Buttigieg
,
A. Gould
,
V. McPhun
,
M. Baker
Journal of Biological Chemistry
1998
Corpus ID: 8641117
The physiological roles of plasminogen activator inhibitor-2 (PAI-2) are not yet well understood. Kinetic studies suggest a role…
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1997
1997
Plasminogen activators play an essential role in extracellular‐matrix invasion by lymphoblastic T cells
Lars S. Reiter
,
O. Spertini
,
E. Kruithof
International Journal of Cancer
1997
Corpus ID: 11235251
Involvement of extravascular sites, in particular infiltration of the central nervous system, is a frequent complication of T…
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1996
1996
Prognostic relevance of urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitors PAI-1 and PAI-2 in gastric cancer
H. Ito
,
Yutaka Yonemura
,
+7 authors
Takuma Sasaki
Virchows Archiv
1996
Corpus ID: 34674953
Expression of urokinase-type plasminogen activator (uPA), plasminogen activator inhibitor-1 (PAI-1) and plasminogen activator…
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1995
1995
Characterization and chromosomal localization of ELANH2, the gene encoding human monocyte/neutrophil elastase inhibitor.
Erica Evans
,
J. Cooley
,
Eileen Remold-O'Donnell
Genomics
1995
Corpus ID: 45802355
Human monocyte/neutrophil elastase inhibitor (HEI) is a protease inhibitor of the serpin superfamily that rapidly inactivates…
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1995
1995
Evaluation of the fibrinolytic system in full-term neonates
A. Pinacho
,
J. Paramo
,
M. Ezcurdia
,
E. Rocha
International journal of clinical & laboratory…
1995
Corpus ID: 25108115
SummaryPlasminogen activity and antigen, euglobulin fibrinolytic activity, tissue-type plasminogen activator activity and antigen…
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1989
1989
Stimulation of plasminogen activator inhibitor activity in human monocytes infected with dengue virus.
C. Krishnamurti
,
L. Wahl
,
B. Alving
American Journal of Tropical Medicine and Hygiene
1989
Corpus ID: 25641798
Human monocytes, in an essentially serum-free culture medium, were infected with dengue 2 virus in the presence of sub…
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1989
1989
Variants of human tissue-type plasminogen activator substituted at the protease cleavage site and glycosylation sites, and truncated at the N- and C-termini.
N. Haigwood
,
G. Mullenbach
,
+6 authors
E. Pâques
Protein Engineering
1989
Corpus ID: 25713024
Mutations were directed to specific regions of the human tissue-type plasminogen activator (t-PA) gene in an effort to better…
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