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Piribedil

Known as: Piribedil [Chemical/Ingredient], Piribendyl, Pyrimidine, 2-(4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl)- 
A dopamine D2 agonist. It is used in the treatment of parkinson disease, particularly for alleviation of tremor. It has also been used for… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Apathy is one of the most common symptoms encountered in Parkinson's disease, and is defined as a lack of motivation accompanied… Expand
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Review
2013
Review
2013
Subtype-Selective Agents: Potential Therapeutics for Neurological and Psychiatric Disorders Na Ye,† John L. Neumeyer,‡ Ross J… Expand
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Highly Cited
2009
Highly Cited
2009
The alkylation of amines by alcohols has been achieved using 0.5 mol % [Ru(p-cymene)Cl(2)](2) with the bidentate phosphines dppf… Expand
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Highly Cited
2002
Highly Cited
2002
Because little comparative information is available concerning receptor profiles of antiparkinson drugs, affinities of 14 agents… Expand
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Review
2002
Review
2002
Current research in Parkinson’s disease (PD) focuses on symptomatic therapy and neuroprotective interventions. Drugs that have… Expand
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2002
2002
Piribedil is a dopamine agonist acting on D2 and D3 central nervous system dopamine receptors. This drug has been administered to… Expand
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Highly Cited
2001
Highly Cited
2001
Modification of the dissolution rate and, thus, the enhancement of the bioavailability of a dopaminergic drug, piribedil, which… Expand
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Highly Cited
2000
Highly Cited
2000
Three patients with Parkinson's disease had so-called sleep attacks at the wheel while taking bromocryptine, lisuride pergolide… Expand
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Highly Cited
1986
Highly Cited
1986
  • W. Woolverton
  • Pharmacology Biochemistry and Behavior
  • 1986
  • Corpus ID: 10456186
Rhesus monkeys were surgically prepared with chronic intravenous catheters and allowed to self-administer the indirect dopamine… Expand
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Highly Cited
1974
Highly Cited
1974
Unilateral radiofrequency lesions or chemical lesions with 6-hydroxydopamine were produced in the substantia nigra of rat brain… Expand
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