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Piribedil

Known as: Piribedil [Chemical/Ingredient], Piribendyl, Pyrimidine, 2-(4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl)- 
A dopamine D2 agonist. It is used in the treatment of parkinson disease, particularly for alleviation of tremor. It has also been used for… 
National Institutes of Health

Related topics

Related topics

13 relations

Broader (2)

Antiparkinson AgentsDopamine Agonists

Narrower (4)

ET-495Piribedil HydrochloridePiribedil MesylateTrivastal
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
Action of neuroleptics and antidepressants on the hypothermia produced by dopaminomimetics apomorphine and piribedil in mice
Neuroleptics, antidepres ants and anticholinergics were compared in their action on the hypothermia produced by apomorphine (AP… 
1986
1986
Piribedil Test in Migraine: Neruoendocrinological Aspects
SYNOPSIS 
1985
1985
Higher CSF levels of HVA and 5-HIAA in delusional compared to nondelusional depression.
To the Editor.— The possible biochemical heterogeneity of affective disorders has been discussed during the last decade. 1 The… 
1985
1985
The effect of dopamine, apomorphine and piribedil on the mesenterial blood flow of the cat.
Responses to i.v. administration of dopamine, apomorphine, piribedil and bromocriptine were investigated in the feline mesenteric… 
Highly Cited
1984
Highly Cited
1984
Separation of peripheral dopamine receptors by a selective DA1 antagonist, SCH 23390.
Intravenous (i.v.) infusions of SCH 23390 (R-(+)-8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepine-7- ol) produced… 
1978
1978
Catecholaminergic regulation of TSH and growth hormone release in ovariectomized and ovariectomized, steroid-primed rats.
Third ventricular injection of dopamine (DA), Piribedil (ET-495), a DA receptor stimulator, norepinephrine (NE), epinephrine (E… 
1977
1977
The effect of piribedil on body temperature in mice and rats.
Piribedil produces a pronounced hypothermia both in mice and rats. This hypothermia was prevented by previous administration of… 
Highly Cited
1976
Highly Cited
1976
Influence of dopaminergic agonists and antagonists on serum prolactin concentrations in the rat.
Inhibitors of dopaminergic neurotransmission, such as reserpine (RES), given alone or combined with alpha-methyl-p-tyrosine… 
1975
1975
Drug interactions with dopamin-stimulated adenylate cyclasses of caudate nucleus and retina: direct agonist effect of a piribedil metabolite.
Dopamine- and apomorphine-stimulated adenylate cyclase activity, which is antagonized by neuroleptic drugs (pimozide… 
1975
1975
Levels of piribedil and its active metabolite (S-584) in the rat striatum.
1. A gas chromatographic-mass fragmentographic method has been developed to determine piribedil and its metabolite S-584, using…