Piribedil

Known as: Piribedil [Chemical/Ingredient], Piribendyl, Pyrimidine, 2-(4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl)- 
A dopamine D2 agonist. It is used in the treatment of parkinson disease, particularly for alleviation of tremor. It has also been used for… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Apathy is one of the most common symptoms encountered in Parkinson's disease, and is defined as a lack of motivation accompanied… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • table 2
Is this relevant?
2006
2006
The dopamine D2/D3 receptor agonist and alpha2 adrenergic receptor antagonist, piribedil, is used clinically as monotherapy and… (More)
Is this relevant?
2006
2006
Cognitive deficits are often associated with motor symptoms in Parkinson's disease. This study investigates the ability of… (More)
  • figure 2
  • figure 1
  • figure 4
  • figure 3
  • table 1
Is this relevant?
2003
2003
'Sleep attacks', episodes of sudden onset of sleep without any prodromal symptoms, were initially described in patients with… (More)
Is this relevant?
2002
2002
Piribedil is a dopamine agonist acting on D2 and D3 central nervous system dopamine receptors. This drug has been administered to… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Because little comparative information is available concerning receptor profiles of antiparkinson drugs, affinities of 14 agents… (More)
  • table 1
  • table 2
  • table 3
  • table 4
  • table 5
Is this relevant?
2001
2001
OBJECTIVE Age-related decrease in dopamine D(2) receptors is associated with cognitive decline in healthy elderly individuals… (More)
Is this relevant?
Highly Cited
1986
Highly Cited
1986
Rhesus monkeys were surgically prepared with chronic intravenous catheters and allowed to self-administer the indirect dopamine… (More)
Is this relevant?
1975
1975
We studied the biochemical and pharmacologic modes of action of piribedil and apomorphine in the rat. Although both drugs have… (More)
Is this relevant?
1974
1974
Unilateral radiofrequency lesions or chemical lesions with 6-hydroxydopamine were produced in the substantia nigra of rat brain… (More)
  • table 2
  • table 3
  • figure 1
Is this relevant?