Phosphoenolpyruvate carboxykinase deficiency

Known as: Phosphoenolpyruvate Carboxykinase (GTP) Deficiency, PCK1 DEFICIENCY, CYTOSOLIC, Phosphopyruvate carboxylase deficiency 
A very rare, autosomal recessive inherited disorder caused by deficiency of the enzyme phosphoenolpyruvate carboxykinase, which is involved in… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Insulin resistance is a major risk factor for type 2 diabetes mellitus. The protein encoded by the sirtuin 1 (Sirt1) gene, which… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2009
2009
Pancreatic beta-cells couple the oxidation of glucose to the secretion of insulin. Apart from the canonical K(ATP)-dependent… (More)
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Epidemiological studies linking low birth weight and subsequent cardiometabolic disease have given rise to the hypothesis that… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • table 2
Is this relevant?
Highly Cited
2003
Highly Cited
2003
The control of lipid and glucose metabolism is closely linked. The nuclear receptors liver X receptor (LXR)alpha and LXR beta… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 3
  • figure 5
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Glucocorticoid hormones, acting via nuclear receptors, regulate many metabolic processes, including hepatic gluconeogenesis. It… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • table 1
Is this relevant?
Highly Cited
1994
Highly Cited
1994
An increase in hepatic gluconeogenesis is believed to be an important factor responsible for the fasting hyperglycemia detected… (More)
  • figure 1
  • figure 3
  • figure 2
  • figure 4
Is this relevant?
1991
1991
The sibling of a patient in whom a diagnosis of phosphoenolpyruvate carboxykinase had been made developed a similar clinical… (More)
  • table 1
Is this relevant?
1986
1986
A 3-month-old girl presented with anorexia, failure to thrive and drowsiness. She was mildly icteric with hepatomegaly and… (More)
  • table 1
  • table 2
  • figure 1
Is this relevant?
1976
1976
Two children are described who suffered from hypoglycemia and liver impairment. Assays of gluconeogenic enzymes in liver samples… (More)
Is this relevant?
Highly Cited
1967
Highly Cited
1967
1. Phosphoenolpyruvate carboxykinase and pyruvate carboxylase were measured in foetal, newborn and adult rat liver extracts by a… (More)
  • table 1
  • table 2
  • figure 1
  • table 3
  • figure 2
Is this relevant?