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Phosphoenolpyruvate carboxykinase deficiency

Known as: Phosphoenolpyruvate Carboxykinase (GTP) Deficiency, PCK1 DEFICIENCY, CYTOSOLIC, Phosphopyruvate carboxylase deficiency 
A very rare, autosomal recessive inherited disorder caused by deficiency of the enzyme phosphoenolpyruvate carboxykinase, which is involved in… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Cancer cells display a high rate of glycolysis in the presence of oxygen to promote proliferation. Gluconeogenesis, the reverse… Expand
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Highly Cited
2005
Highly Cited
2005
Epidemiological studies linking low birth weight and subsequent cardiometabolic disease have given rise to the hypothesis that… Expand
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Highly Cited
2003
Highly Cited
2003
The liver plays several critical roles in the metabolic adaptation to fasting. We have shown previously that the transcriptional… Expand
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Highly Cited
2003
Highly Cited
2003
The control of lipid and glucose metabolism is closely linked. The nuclear receptors liver X receptor (LXR)α and LXRβ have been… Expand
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Highly Cited
2002
Highly Cited
2002
The effects of heavy metals on growth, intermediary metabolism and enzyme activities were investigated in yellow perch (Perca… Expand
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Review
1998
Review
1998
In most cases, the genetic susceptibility to Type 2 diabetes fails to follow simple Mendelian inheritance, consistent with the… Expand
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Highly Cited
1997
Highly Cited
1997
Glucocorticoid hormones, acting via nuclear receptors, regulate many metabolic processes, including hepatic gluconeogenesis. It… Expand
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Highly Cited
1994
Highly Cited
1994
An increase in hepatic gluconeogenesis is believed to be an important factor responsible for the fasting hyperglycemia detected… Expand
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Highly Cited
1967
Highly Cited
1967
1. Phosphoenolpyruvate carboxykinase and pyruvate carboxylase were measured in foetal, newborn and adult rat liver extracts by a… Expand
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Highly Cited
1963
Highly Cited
1963
Because of the strongly exergonic nature of glycolysis, the formation of carbohydrate from lactate and pyruvate does not proceed… Expand
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