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Pharmacogenomics

Known as: MOLPATH.PHARMG, PGx, pharmacogenomic 
The study of how a person's genes affect the way he or she responds to drugs. Pharmacogenomics is being used to learn ahead of time what the best… 
National Institutes of Health

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Medication usage suggestion:Imp:Pt:^Patient:NarMedication usage suggestion:Type:Pt:^Patient:NomPharmacogenetics

Papers overview

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2013
2013
Genotypic variation in the SV2C gene impacts response to atypical antipsychotics the CATIE Study
2012
2012
Identifying aberrant pathways through integrated analysis of knowledge in pharmacogenomics
MOTIVATION Many complex diseases are the result of abnormal pathway functions instead of single abnormalities. Disease diagnosis… 
Review
2012
Review
2012
A recent update of pharmacogenomics in drug-induced severe skin reactions.
In some adverse drug reactions (ADRs), genetic predisposition plays a significant role in pathogenesis, and the skin is the most… 
Review
2010
Review
2010
The Pharmacogenomics of Membrane Transporters Project: Research at the Interface of Genomics and Transporter Pharmacology
Since the cloning of the first membrane transporter, our understanding of the role of transporters in clinical drug disposition… 
Highly Cited
2010
Highly Cited
2010
Author ' s personal copy Using text to build semantic networks for pharmacogenomics
Most pharmacogenomics knowledge is contained in the text of published studies, and is thus not available for automated… 
Review
2010
Review
2010
Decision criteria for rational selection of homogeneous genotyping platforms for pharmacogenomics testing in clinical diagnostics
Abstract Background: Genotyping is crucial for the identification of genetic markers underlying the development of neoplastic… 
Review
2004
Review
2004
Pharmacogenomics: the influence of genomic variation on drug response.
Unpredictable efficacy and toxicity are major hurdles in the administration of many medications. By identifying inherited DNA… 
Review
2003
Review
2003
Human inter-individual DNA sequence variation in candidate genes, drug targets, the importance of haplotypes and pharmacogenomics.
The identification of genes predisposing to human diseases is of paramount importance for understanding the molecular basis of… 
Review
2003
Review
2003
Arylamine N-acetyltransferases: a pharmacogenomic approach to drug metabolism and endogenous function.
The arylamine N-acetyltransferases (NATs) are a unique family of enzymes that catalyse the transfer of an acetyl group from… 
Review
2001
Review
2001
No pain relief from codeine...? An introduction to pharmacogenomics.
Drug treatment remains a mainstay of medicine. In some situations a drug unexpectedly has no effect, or unforeseen serious side… 
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