Peripheral Tolerance

Known as: Tolerance, Peripheral 
The mechanism, in peripheral lymphoid organs (LYMPH NODES; SPLEEN; TONSILS; and mucosal-associated lymphoid tissue), that prevents mature lymphocytes… (More)
National Institutes of Health

Papers overview

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Review
2008
Review
2008
Classically, the CD28/cytotoxic T-lymphocyte antigen-4 (CTLA-4) and B7 families of cell surface molecules regulate complex… (More)
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Highly Cited
2006
Highly Cited
2006
Contrary to the proinflammatory role of mast cells in allergic disorders, the results obtained in this study establish that mast… (More)
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Highly Cited
2004
Highly Cited
2004
Regulatory T (Treg) cells mediate homeostatic peripheral tolerance by suppressing autoreactive T cells. Failure of host antitumor… (More)
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Review
2002
Review
2002
The immune system generally avoids horror autotoxicus or autoimmunity, an attack against the body's own constituents. This… (More)
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Highly Cited
2001
Highly Cited
2001
Dendritic cells (DCs) have the capacity to initiate immune responses, but it has been postulated that they may also be involved… (More)
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Highly Cited
2001
Highly Cited
2001
PTEN, a tumor suppressor gene, is essential for embryogenesis. We used the Cre-loxP system to generate a T cell-specific deletion… (More)
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Highly Cited
1999
Highly Cited
1999
The mechanisms of allograft tolerance have been classified as deletion, anergy, ignorance and suppression/regulation. Deletion… (More)
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Highly Cited
1995
Highly Cited
1995
Approximately 10% of peripheral CD4+ cells and less than 1% of CD8+ cells in normal unimmunized adult mice express the IL-2… (More)
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Highly Cited
1994
Highly Cited
1994
An adoptive transfer system was used to monitor physically the behavior of a trace population of TCR transgenic T cells in vivo… (More)
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Highly Cited
1994
Highly Cited
1994
Experimental autoimmune encephalomyelitis (EAE) is a cell-mediated autoimmune disease that serves as an animal model for multiple… (More)
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