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Peripheral Tolerance

Known as: Tolerance, Peripheral 
The mechanism, in peripheral lymphoid organs (LYMPH NODES; SPLEEN; TONSILS; and mucosal-associated lymphoid tissue), that prevents mature lymphocytes… 
National Institutes of Health

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aspects of radiation effectsphysiological aspects

Papers overview

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Review
2010
Review
2010
Mechanisms maintaining peripheral tolerance
The presentation of self-peptide–MHC complexes in the periphery to potentially autoreactive T cells that have escaped negative… 
Highly Cited
2006
Highly Cited
2006
Mast cells are essential intermediaries in regulatory T-cell tolerance
Contrary to the proinflammatory role of mast cells in allergic disorders, the results obtained in this study establish that mast… 
Highly Cited
2005
Highly Cited
2005
Resting dendritic cells induce peripheral CD8+ T cell tolerance through PD-1 and CTLA-4
T cells recognizing self proteins exist without causing autoimmunity in healthy individuals. These autoreactive T cells are kept… 
Review
2003
Review
2003
Dendritic Cell Function in Vivo during the Steady State: A Role in Peripheral Tolerance
Abstract: The avoidance of autoimmunity requires mechanisms to actively silence or tolerize self reactive T cells in the… 
Review
2002
Review
2002
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
The immune system generally avoids horror autotoxicus or autoimmunity, an attack against the body's own constituents. This… 
Highly Cited
2001
Highly Cited
2001
T cell-specific loss of Pten leads to defects in central and peripheral tolerance.
Highly Cited
1999
Highly Cited
1999
Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance
The mechanisms of allograft tolerance have been classified as deletion, anergy, ignorance and suppression/regulation. Deletion… 
Review
1997
Review
1997
The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD.
Highly Cited
1994
Highly Cited
1994
Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis.
Experimental autoimmune encephalomyelitis (EAE) is a cell-mediated autoimmune disease that serves as an animal model for multiple… 
Highly Cited
1991
Highly Cited
1991
Ablation of “tolerance” and induction of diabetes by virus infection in viral antigen transgenic mice
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