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Peripheral Tolerance

Known as: Tolerance, Peripheral 
The mechanism, in peripheral lymphoid organs (LYMPH NODES; SPLEEN; TONSILS; and mucosal-associated lymphoid tissue), that prevents mature lymphocytes… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Regulatory T cells (Tregs) are important for the induction and maintenance of peripheral tolerance therefore, they are key in… Expand
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Review
2019
Review
2019
Regulatory T (Treg) cells represent an essential component of peripheral tolerance. Given their potently immunosuppressive… Expand
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Review
2018
Review
2018
Adoptive cell transfer using chimeric antigen receptors (CAR) has emerged as one of the most promising new therapeutic modalities… Expand
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Review
2018
Review
2018
The pathogenesis of autoimmunity remains to be fully elucidated, although the contribution of genetic and environmental factors… Expand
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Review
2018
Review
2018
Regulatory T (Treg) cells represent a subpopulation of suppressor CD4+ T cells critically involved in the establishment of… Expand
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Highly Cited
2004
Highly Cited
2004
Regulatory T (Treg) cells mediate homeostatic peripheral tolerance by suppressing autoreactive T cells. Failure of host antitumor… Expand
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Review
2002
Review
2002
The immune system generally avoids horror autotoxicus or autoimmunity, an attack against the body's own constituents. This… Expand
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Highly Cited
2001
Highly Cited
2001
PTEN, a tumor suppressor gene, is essential for embryogenesis. We used the Cre-loxP system to generate a T cell-specific deletion… Expand
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Highly Cited
1995
Highly Cited
1995
Approximately 10% of peripheral CD4+ cells and less than 1% of CD8+ cells in normal unimmunized adult mice express the IL-2… Expand
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Highly Cited
1994
Highly Cited
1994
Experimental autoimmune encephalomyelitis (EAE) is a cell-mediated autoimmune disease that serves as an animal model for multiple… Expand
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