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Perindopril

Known as: (2S,3aS,7aS)-1-((S)-N-((S)-1-Carboxybutyl)alanyl)hexahydro-2-indolinecarboxylic Acid, 1-ethyl Ester, Perindopril [Chemical/Ingredient], Perindoprilum 
A non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Upon hydrolysis, perindopril is converted to its… 
National Institutes of Health

Related topics

Related topics

29 relations

Narrower (8)

AceonAmlodipine / PerindoprilIndapamide / PerindoprilPerindopril Erbumine
Amlodipine 10 MG / Perindopril arginine 14 MG Oral TabletAngioedemaAngiotensin-Converting Enzyme Inhibitors [MoA]Congestive heart failure

Broader (2)

Angiotensin-Converting Enzyme InhibitorsAntihypertensive Agents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
Effect of Perindopril on Cerebral and Renal Perfusion on Normotensives in Mild Early Ischaemic Stroke: A Randomized Controlled Trial
Background and Purpose: Blood pressure reduction is central to secondary prevention after stroke, but the optimal time to start… 
2003
2003
Angiotensin-II induces the tissue inhibitor of metalloproteinases-1 through the protein kinase-C signaling pathway in rat liver fibrosis development.
2003
2003
Angiotensin-converting enzyme inhibition but not angiotensin II type 1 receptor antagonism augments coronary release of tissue plasminogen activator in hypertensive patients.
Highly Cited
2003
Highly Cited
2003
Effects of a Perindopril-Based Blood Pressure–Lowering Regimen on Disability and Dependency in 6105 Patients With Cerebrovascular Disease A Randomized Controlled Trial
Background and Purpose— We sought to quantify the effects of blood pressure lowering on long-term disability and dependency among… 
2002
2002
Perindopril Effect on Uncoupling Protein and Energy Metabolism in Failing Rat Hearts
Uncoupling proteins, inner mitochondrial membrane proton transporters, are important for regulating myocardial energy efficiency… 
Highly Cited
2000
Highly Cited
2000
Reducing premature death and renal failure in Australian Aboriginals
To describe results of a systematic treatment program to modify renal and cardiovascular disease in an Aboriginal community whose… 
Highly Cited
1996
Highly Cited
1996
Endothelium-dependent relaxation in resistance arteries from spontaneously hypertensive rats: effect of long-term treatment with perindopril, quinapril, hydralazine or amlodipine
Objective To examine the effects of different types of anti hypertensive treatment on endothelium-dependent relaxation in… 
1995
1995
Comparison of effects of ACE inhibition with calcium channel blockade on renal disease in a model combining genetic hypertension and diabetes.
1994
1994
BLOOD PRESSURE AND LIFESPAN FOLLOWING BRIEF ACE INHIBITOR TREATMENT IN YOUNG SPONTANEOUSLY HYPERTENSIVE RATS
1. Brief treatment with angiotensin‐converting enzyme (ACE) inhibitors in young spontaneously hypertensive rats (SHR) causes a… 
1992
1992
ACUTE AND CHRONIC EFFECTS OF ANGIOTENSIN‐CONVERTING ENZYME INHIBITORS ON TISSUE ANGIOTENSIN‐CONVERTING ENZYME
1. The effects of angiotensin‐converting enzyme (ACE) inhibitors on the tissue ACE were assessed by quantitative in vitro… 
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