Peptidomimetics

Compounds that are designed to mimic the 3D structure of a natural peptide or protein.
National Institutes of Health

Papers overview

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Review
2015
Review
2015
The purpose of this paper is to introduce and highlight a few classes of traditional antimicrobial peptides with a focus on… (More)
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2013
2013
Mixed lineage leukemia 1 (MLL1) is a histone H3 lysine 4 (H3K4) methyltransferase, and targeting the MLL1 enzymatic activity has… (More)
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2011
2011
This paper concerns peptidomimetic scaffolds that can present side chains in conformations resembling those of amino acids in… (More)
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Review
2011
Review
2011
Despite their enormous diversity in biological function and structure, peptides and proteins are endowed with properties that… (More)
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Review
2008
Review
2008
The demand for modified peptides with improved stability profiles and pharmacokinetic properties is driving extensive research… (More)
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2008
2008
A series of synthetic antimicrobial peptidomimetics (SAMPs) have been prepared and found to be highly active against several Gram… (More)
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Highly Cited
2006
Highly Cited
2006
Small peptide-based agents have attracted wide interest as cancer-targeting agents for diagnostic imaging and targeted therapy… (More)
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2006
2006
Apart from genetically programmed cell aging, different external aggressors related to oxidative stress and lipid peroxidation… (More)
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2006
2006
The major impediment to cure for many malignancies is the development of therapy resistance with resultant tumor progression… (More)
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2002
2002
Members of the erbB family receptor tyrosine kinases (erbB1, erbB2, erbB3, and erbB4) are overexpressed in a variety of human… (More)
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