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Patched Receptors

Known as: Receptor, Patched, Patched Sonic Hedgehog Receptors, Patched Receptor 
A family of 12-pass transmembrane proteins originally identified in Drosophila that are receptors for HEDGEHOG PROTEINS. They have important roles in… 
National Institutes of Health

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Protein Patched Homolog 1, human

Papers overview

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2014
2014
Patched Targeting Peptides for Imaging and Treatment of Hedgehog Positive Breast Tumors
High tumor hedgehog expression is correlated with poor prognosis in invasive ductal carcinoma. Peptides which bind the patched… 
2012
2012
Splicing aberration in naevoid basal cell carcinoma syndrome.
2010
2010
Culturing Saccharomyces cerevisiae yeast strain expressing human functional patched protein, comprises cloning sequences in yeast expression vector, transforming yeasts with vector and culturing…
2009
2009
Tumorigenesis: No frills attached
2008
2008
Two Patched Protein Subtypes and a Conserved Domain of Group I Proteins That Regulates Turnover*
Patched (Ptc) is a 12-cross membrane protein that binds the secreted Hedgehog protein. Its regulation of the Hedgehog signaling… 
2007
2007
176 SONIC HEDGEHOG ESTABLISHES THE FIBROBLAST GROWTH FACTORS RESPONSIVENESS IN THE LIMB BUD SHH-FGF FEEDBACK LOOP.
Limb outgrowth is initiated and maintained by the secretion of FGFs in the apical ectodermal ridge (AER), whereas progressive… 
Highly Cited
1999
Highly Cited
1999
Cholesterol Biosynthesis from Lanosterol
The cDNA encoding the 471-amino acid rat 7-dehydrocholesterol reductase (DHCR), an enzyme that has been implicated in both… 
1982
1982
Participation of calmodulin in immunoglobulin capping
When mouse B lymphocytes are incubated with antibodies against their surface immunoglobulin (Ig), patching and capping occur in a… 
1980
1980
Metabolic and cytoskeletal modulation of transferrin receptor mobility in mitogen-activated human lymphocytes.
The transferrin receptors which appear on mitogen-activated human peripheral blood lymphocytes were found by the use of… 
1979
1979
Lipid domains in biological membranes: their structural and functional perturbation by free fatty acids and the regulation of receptor mobility. Co-presidential address.
We have studied the interaction of free fatty acids (FFAs) with cell membranes and lipid bilayers by monitoring changes in the… 
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