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Paroxetine

Known as: (3S-trans)-3-((1,3-Benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine, Paroxetine [Chemical/Ingredient], (-)-(3S,4R)-4-(P-Fluorophenyl)-3-((3,4-(methylenedioxy)phenoxy)methyl)piperidine 
A serotonin uptake inhibitor that is effective in the treatment of depression.
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
BACKGROUND Tamoxifen, a selective estrogen receptor modulator (SERM), is converted to 4-hydroxy-tamoxifen and other active… Expand
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Highly Cited
2003
Highly Cited
2003
BACKGROUND & AIMS Psychotherapy and antidepressants are effective in patients with severe irritable bowel syndrome (IBS), but the… Expand
Highly Cited
2003
Highly Cited
2003
BACKGROUND Animal studies have shown that stress is associated with damage to the hippocampus, inhibition of neurogenesis, and… Expand
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Highly Cited
2002
Highly Cited
2002
We have previously shown that the risk of major depression in patients with malignant melanoma undergoing interferon-α (IFN… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Depression commonly complicates treatment with the cytokine interferon alfa-2b. Laboratory animals pretreated with… Expand
Highly Cited
2001
Highly Cited
2001
OBJECTIVE To compare paroxetine with placebo and imipramine with placebo for the treatment of adolescent depression. METHOD… Expand
Highly Cited
2001
Highly Cited
2001
OBJECTIVE Depression is commonly associated with frontal hypometabolic activity accompanied by hypermetabolism in certain limbic… Expand
Highly Cited
2001
Highly Cited
2001
BACKGROUND In functional brain imaging studies of major depressive disorder (MDD), regional abnormalities have been most commonly… Expand
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Review
1999
Review
1999
It is now nearly 5 years since the last of the currently recognised 5-HT receptors was identified in terms of its cDNA sequence… Expand
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Highly Cited
1990
Highly Cited
1990
&NA; The effect of the selective serotonin reuptake inhibitor paroxetine on diabetic neuropathy symptoms was examined in… Expand