Paroxetine

Known as: (3S-trans)-3-((1,3-Benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine, Paroxetine [Chemical/Ingredient], (-)-(3S,4R)-4-(P-Fluorophenyl)-3-((3,4-(methylenedioxy)phenoxy)methyl)piperidine 
A serotonin uptake inhibitor that is effective in the treatment of depression.
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
BACKGROUND Tamoxifen, a selective estrogen receptor modulator (SERM), is converted to 4-hydroxy-tamoxifen and other active… (More)
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Highly Cited
2003
Highly Cited
2003
CONTEXT Standard therapy for hot flashes has been hormone replacement with estradiol or progestational agents, but recent data… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Animal studies have shown that stress is associated with damage to the hippocampus, inhibition of neurogenesis, and… (More)
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Highly Cited
2002
Highly Cited
2002
We have previously shown that the risk of major depression in patients with malignant melanoma undergoing interferon-α (IFN… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Depression commonly complicates treatment with the cytokine interferon alfa-2b. Laboratory animals pretreated with… (More)
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Highly Cited
2001
Highly Cited
2001
OBJECTIVE Depression is commonly associated with frontal hypometabolic activity accompanied by hypermetabolism in certain limbic… (More)
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Highly Cited
2001
Highly Cited
2001
OBJECTIVE To compare paroxetine with placebo and imipramine with placebo for the treatment of adolescent depression. METHOD… (More)
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Highly Cited
2000
Highly Cited
2000
The relationship of the serotonin transporter gene promoter region polymorphism (5-HTTLPR) to antidepressant response was… (More)
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Highly Cited
1999
Highly Cited
1999
Previous positron emission tomography (PET) studies of patients with obsessive-compulsive disorder (OCD) have found elevated… (More)
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Highly Cited
1990
Highly Cited
1990
The effect of the selective serotonin reuptake inhibitor paroxetine on diabetic neuropathy symptoms was examined in comparison to… (More)
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