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Effects of morphine in decomposing bodies on the development of Lucilia sericata (Diptera: Calliphoridae).
TLDR
Results of this study show that an underestimation of the postmortem interval of 24 h is possible if the presence of morphine in tissues is not considered, demonstrating the necessity of considering the possible effects of drugs in tissues on insect growth rates when estimating the post autopsy interval using entomological techniques. Expand
Morphine extraction in necrophagous insects remains for determining ante-mortem opiate intoxication.
TLDR
Remains of necrophagous insects, particularly puparial cases, are often preserved for a long time, and consequently can serve as late alternative specimens for toxicological analysis when suitable tissues are not available. Expand
Profiling gene expression of whole cytochrome P450 superfamily in human bronchial and peripheral lung tissues: Differential expression in non-small cell lung cancers.
TLDR
Different CYP expression patterns between bronchial mucosa and pulmonary parenchyma that indicate distinctive susceptibility of these tissues toward the deleterious effects of inhaled chemical toxicants and carcinogens are highlighted. Expand
Entomofauna of buried bodies in northern France
TLDR
This study concerns insects sampled on 22 exhumed cadavers in the Lille area, where three species were regularly found because of their preference for underground environments or closed environments. Expand
Involvement of UDP-Glucuronosyltransferases UGT1A9 and UGT2B7 in Ethanol Glucuronidation, and Interactions with Common Drugs of Abuse
TLDR
The results suggest that cannabinol and cannabidiol could significantly alter ethanol glucuronidation, and UGT1A9 and 2B7 are the main enzymes involved in ethanol glucuridation. Expand
Determination of drug levels in larvae of Lucilia sericata (Diptera: Calliphoridae) reared on rabbit carcasses containing morphine.
TLDR
Concentrations of morphine in larvae reared on rabbit carcasses containing morphine were 30 to 100 times lower than the concentrations found in the tissues, and correlations were found between administered dosages, tissue concentrations and younger larvae, prepuparial larvae or puparia. Expand
Determination of drug levels in two species of necrophagous Coleoptera reared on substrates containing morphine.
TLDR
The potential for use of necrophagous Coleoptera, as well as Diptera larvae, as alternate specimens for toxicological analyses is demonstrated and concentrations correlated with cadaveric tissue concentrations during larval stages and to a lesser extent in the adult stage are demonstrated. Expand
CYP2A13 genetic polymorphism in French Caucasian, Gabonese and Tunisian populations
TLDR
These findings provide data for further studies that associate CYP2A13 haplotypes with an incidence of smoking-related tumours in respect of ethnicity andmarked inter-ethnic variations in CYP1A13 were identified and confirmed. Expand
Morphine perfused rabbits: a tool for experiments in forensic entomotoxicology.
TLDR
The kinetics of morphine elimination from blood after a single intravenous injection of morphine and the concentration of morphine in tissues following a continuous perfusion were studied to obtain controlled morphine tissue concentrations similar to those encountered in fatal human heroin overdoses. Expand
Use of Hair Testing to Determine Methadone Exposure in Pediatric Deaths
TLDR
A case of death attributed to methadone acute poisoning in an infant aged 11 months is reported, and the cause of death was determined to be acute “methadone poisoning” and the manner ofdeath was “accidental”. Expand
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