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PYRUVATE CARBOXYLASE

Known as: pyruvic carboxylase, Carboxylase, Pyruvate, Pyruvate:carbon-dioxide ligase (ADP-forming) 
A biotin-dependent enzyme belonging to the ligase family that catalyzes the addition of CARBON DIOXIDE to pyruvate. It is occurs in both plants and… 
National Institutes of Health

Related topics

Related topics

16 relations
In BloodPC genePODXL geneProcess of secretion

Broader (1)

Ligase

Papers overview

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1985
1985
Distribution and degradation of biotin-containing carboxylases in human cell lines.
Incubation of cultured cells with [3H]biotin leads to the labelling of acetyl-CoA carboxylase, pyruvate carboxylase, propionyl… 
1983
1983
Inhibition of pyruvate carboxylase degradation and total protein breakdown by lysosomotropic agents in 3T3-L1 cells.
1. Exposure to [3H]biotin during the differentiation of 3T3-L1 cells to adipocytes selectively labelled pyruvate carboxylase (EC… 
1980
1980
Biotin status, blood pyruvate carboxylase (EC 6.4.1.1) activity and performance in broilers under different conditions of bird husbandry and diet processing
1. Three experiments were conducted to investigate the relationships between blood pyruvate carboxylase (pyruvate: carbon dioxide… 
1979
1979
Pyruvate carboxylase from a thermophilic Bacillus: some molecular characteristics.
Analysis of the native enzyme and of the subunits produced upon its denaturation shows that pyruvate carboxylase from a… 
1974
1974
The Pyruvate Carboxylase of Verticillium albo-atrum
The pyruvate carboxylase of Verticillium albo-atrum had a pH optimum of 7·8 and a specific requirement for ATP. At the optimum pH… 
1973
1973
Regulation of pyruvate metabolism via pyruvate carboxylase in rat brain mitochondria.
1. The fixation of CO(2) by pyruvate carboxylase in isolated rat brain mitochondria was investigated. 2. In the presence of… 
Highly Cited
1969
Highly Cited
1969
Intracellular localization of pyruvate carboxylase and phosphoenolpyruvate carboxykinase in rat liver.
The overall activity and distribution of pyruvate carboxylase and of phosphoenolpyruvate carboxykinase in rat liver was studied… 
Highly Cited
1966
Highly Cited
1966
Pyruvate carboxylase. 8. The subunit structure as examined by electron microscopy.
Highly Cited
1964
Highly Cited
1964
MODE OF ACTION OF GLUCOCORTICOIDS. I. STIMULATION OF GLUCONEOGENESIS INDEPENDENT OF SYNTHESIS DE NOVO OF ENZYMES.
The adrenal glucocorticoids regulate carbohydrate formation and protein synthesis (l-6), but the mechanism by which they… 
1947
1947
Fixation of carbon dioxide by a plant oxalacetate carboxylase.
The presence of an oxalacetate carboxylase in parsley root has been reported previously from this laboratory.’ The reaction…