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PWWP Domain

Around 70 amino acids and weakly conserved, the PWWP Domain is named after a conserved Pro-Trp-Trp-Pro motif often found as multiple copies in… Expand
National Institutes of Health

Papers overview

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2017
2017
The human hepatoma-derived growth factor (HDGF), containing the chromatin-associated N-terminal PWWP domain capable of binding… Expand
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Review
2014
Review
2014
PWWP domain-containing proteins are often involved in chromatin-associated biological processes, such as transcriptional… Expand
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Highly Cited
2013
Highly Cited
2013
BackgroundRecognition of histone modifications by specialized protein domains is a key step in the regulation of DNA-mediated… Expand
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2012
2012
Methylation of H4K20 (Lys(20) of histone H4) plays an important role in the regulation of diverse cellular processes. In fission… Expand
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2011
2011
Nearly all cellular and disease related functions of the transcriptional co-activator lens epithelium-derived growth factor… Expand
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Highly Cited
2009
Highly Cited
2009
Methylation of histone H4 lysine 20 (H4K20me) is essential for recruiting checkpoint proteins 53BP1/Crb2 to DNA lesions and… Expand
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2008
2008
Lens epithelium-derived growth factor (LEDGF)/p75 functions as a bimodal tether during lentiviral DNA integration: its C-terminal… Expand
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2008
2008
Integration is an essential step in the retroviral lifecycle, and the lentiviral integrase binding protein lens epithelium… Expand
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2006
2006
Hepatoma Derived Growth Factor (HDGF) is an endogenous nuclear-targeted mitogen that is linked with human disease. HDGF is a… Expand
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Highly Cited
2002
Highly Cited
2002
The PWWP domain is a weakly conserved sequence motif found in >60 eukaryotic proteins, including the mammalian DNA… Expand
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