WHSC1 protein, human

Known as: Wolf-Hirschhorn Syndrome Candidate 1 Protein, NSD2 protein, human, Protein Trithorax-5 
Histone-lysine N-methyltransferase NSD2 (1365 aa, ~152 kDa) is encoded by the human WHSC1 gene. This protein is involved in both histone methylation… (More)
National Institutes of Health

Papers overview

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2014
2014
Karolinska Institutet, Stockholm, Sweden; Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden… (More)
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2013
2013
Epigenetic deregulation of gene expression has a role in the initiation and progression of prostate cancer (PCa). The histone… (More)
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2013
2013
Actively transcribed genes are enriched with the histone variant H3.3. Although H3.3 deposition has been linked to transcription… (More)
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Highly Cited
2011
Highly Cited
2011
The histone lysine methyltransferase NSD2 (MMSET/WHSC1) is implicated in diverse diseases and commonly overexpressed in multiple… (More)
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Highly Cited
2011
Highly Cited
2011
p53-binding protein 1 (53BP1) is known to be an important mediator of the DNA damage response, with dimethylation of histone H4… (More)
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2011
2011
A number of histone methyltransferases have been identified and biochemically characterized, but the pathologic roles of their… (More)
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2008
2008
Dynamic changes in the expression of multiple genes appear to be common features that distinguish transformed cells from their… (More)
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2001
2001
Human interleukin (IL)-5 gene transcription is regulated by several transcription factor binding sites, including CLE 0, GATA… (More)
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Highly Cited
2001
Highly Cited
2001
We describe the isolation and characterization of NSD3, the third member of a gene family including Nsd1 and NSD2. Murine Nsd1… (More)
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2001
2001
We have identified and characterized a gene (60% on protein level) and a pseudogene (93% on DNA level) that show high similarity… (More)
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