DNMT3B protein, human

Known as: DNA (Cytosine-5-)-Methyltransferase 3 Beta, Dnmt3b, DNMT3B Protein 
DNA (cytosine-5)-methyltransferase 3B (853 aa, ~96 kDa) is encoded by the human DNMT3B gene. This protein is involved in DNA methylation.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Epigenetic modification through DNA methylation is implicated in metabolic disease. Using whole-genome promoter methylation… (More)
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Highly Cited
2008
Highly Cited
2008
MicroRNAs (miRNAs) are small noncoding RNA molecules of 20-24 nucleotides that regulate gene expression. In animals, miRNAs form… (More)
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Highly Cited
2006
Highly Cited
2006
DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b cooperatively regulate cytosine methylation in CpG dinucleotides in mammalian… (More)
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Highly Cited
2005
Highly Cited
2005
To explore the role of DNA methylation in the brain, we examined the expression pattern of de novo DNA methyltransferases Dnmt3a… (More)
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Highly Cited
2003
Highly Cited
2003
We have previously shown that the DNA methyltransferases Dnmt3a and Dnmt3b carry out de novo methylation of the mouse genome… (More)
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Highly Cited
2002
Highly Cited
2002
Abnormal methylation and associated silencing of tumor suppressor genes is a common feature of many types of cancers. The… (More)
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Highly Cited
2001
Highly Cited
2001
We demonstrate that the recently identified DNA methyltransferases, Dnmt3a and Dnmt3b, like DNMT1, repress transcription in a… (More)
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Highly Cited
1999
Highly Cited
1999
The establishment of DNA methylation patterns requires de novo methylation that occurs predominantly during early development and… (More)
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Highly Cited
1999
Highly Cited
1999
DNA methylation is an important regulator of genetic information in species ranging from bacteria to humans. DNA methylation… (More)
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Highly Cited
1999
Highly Cited
1999
The putative de novo methyltransferases, Dnmt3a and Dnmt3b, were reported to have weak methyltransferase activity in methylating… (More)
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