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PTX3 protein, human

Known as: TNF Alpha-Induced Protein 5, Pentraxin 3, Pentaxin-Related Protein PTX3 
Pentraxin-related protein PTX3 (381 aa, ~42 kDa) is encoded by the human PTX3 gene. This protein is involved in both inflammation and complement… 
National Institutes of Health

Related topics

Related topics

7 relations
Coiled-Coil DomainExtracellular SpaceLigand BindingPTX3 gene

Broader (1)

PTX3 protein

Papers overview

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Highly Cited
2017
Highly Cited
2017
Serum markers of inflammation and oxidative stress in sarcopenia
BackgroundSarcopenia is a geriatric syndrome characterized by the presence of low muscle mass and function. Possible mechanisms… 
Highly Cited
2014
Highly Cited
2014
Calprotectin (S100A8/9) as serum biomarker for clinical response in proof-of-concept trials in axial and peripheral spondyloarthritis
IntroductionBiomarkers complementing clinical evaluations may help to reduce the length and size of proof-of-concept (PoC) trials… 
Highly Cited
2012
Highly Cited
2012
glucagon-like peptide 1 analog liraglutide reduces TNF-- induced oxidative tress and inflammation in endothelial cells
Objective: Glucagon-like peptide 1 (GLP-1), one of the incretin hormones, has been reported to increase positive inotropic… 
Highly Cited
2011
Highly Cited
2011
Prediction of early, intermediate and late pre‐eclampsia from maternal factors, biophysical and biochemical markers at 11–13 weeks
To develop models for prediction of pre‐eclampsia (PE) based on maternal factors and biophysical and biochemical markers at 11–13… 
Highly Cited
2011
Highly Cited
2011
Pentraxin-3 as a Marker of Disease Activity in Takayasu Arteritis
BACKGROUND Because pentraxin-3 (PTX3) is produced by immune and vascular cells in response to proinflammatory signals, it may be… 
Highly Cited
2011
Highly Cited
2011
Pentraxin 3 is a new inflammatory marker correlated with left ventricular diastolic dysfunction and heart failure with normal ejection fraction.
Highly Cited
2006
Highly Cited
2006
Pentraxin 3 protects from MCMV infection and reactivation through TLR sensing pathways leading to IRF3 activation.
Reactivation of latent human cytomegalovirus (HCMV) following allogeneic transplantation is a major cause of morbidity and… 
Highly Cited
2005
Highly Cited
2005
Human renal epithelial cells produce the long pentraxin PTX3.
BACKGROUND Pentraxin 3 (PTX3) is a prototypic long pentraxin with structural similarities in the C-terminal domain to the… 
Highly Cited
2004
Highly Cited
2004
Modified atherogenic lipoproteins induce expression of pentraxin-3 by human vascular smooth muscle cells.
Highly Cited
2002
Highly Cited
2002
Increased mortality and inflammation in tumor necrosis factor-stimulated gene-14 transgenic mice after ischemia and reperfusion injury.
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