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PTX3 gene

Known as: TSG-14, long pentraxin 3, PENTRAXIN 3 
This gene is involved in complement recognition of pathogens.
National Institutes of Health

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Related topics

5 relations
Ligand BindingPTX3 proteinPTX3 protein, humanPhagocytosis Induction

Papers overview

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Highly Cited
2010
Highly Cited
2010
Proteomic analysis of tumor necrosis factor-alpha-induced secretome of human adipose tissue-derived mesenchymal stem cells.
Human adipose tissue-derived mesenchymal stem cells (hASCs) are useful for regeneration of inflamed or injured tissues. To… 
Review
2009
Review
2009
The long pentraxin PTX3 as a prototypic humoral pattern recognition receptor: interplay with cellular innate immunity
Summary:  The innate immune system consists of a cellular arm and a humoral arm. Components of humoral immunity include diverse… 
Review
2006
Review
2006
Pentraxins as a key component of innate immunity.
Highly Cited
2005
Highly Cited
2005
TNFα-Induced Long Pentraxin PTX3 Expression in Human Lung Epithelial Cells via JNK
Long pentraxin 3 (PTX3), an acute-phase protein, is a newly clarified mediator for innate immunity and inflammation. As a soluble… 
Highly Cited
2004
Highly Cited
2004
PTX3 function as an opsonin for the dectin‐1‐dependent internalization of zymosan by macrophages
Pentraxin 3 (PTX3) is a tumor necrosis factor and interleukin‐1β‐stimulated gene that encodes a long PTX with proinflammatory… 
Highly Cited
2003
Highly Cited
2003
Production of the soluble pattern recognition receptor PTX3 by myeloid, but not plasmacytoid, dendritic cells
PTX3 is a prototypic of long pentraxin consisting of an N‐terminal portion coupled to a C‐terminal pentraxin domain, the latter… 
Highly Cited
2001
Highly Cited
2001
PTX3 in small-vessel vasculitides: an independent indicator of disease activity produced at sites of inflammation.
OBJECTIVE To verify whether the prototypical long pentraxin PTX3 represents an indicator of the activity of small-vessel… 
Highly Cited
2000
Highly Cited
2000
The long pentraxin PTX3 binds to apoptotic cells and regulates their clearance by antigen-presenting dendritic cells.
Pentraxins are acute-phase proteins produced in vivo during inflammatory reactions. Classical short pentraxins, C-reactive… 
Review
1996
Review
1996
Long pentraxins: an emerging group of proteins with diverse functions.
Highly Cited
1994
Highly Cited
1994
Inducible expression of PTX3, a new member of the pentraxin family, in human mononuclear phagocytes.
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