PTPN6 wt Allele

Known as: Protein Tyrosine Phosphatase, Non-Receptor Type 6 wt Allele, SHP-1L, HCPH 
Human PTPN6 wild-type allele is located within 12p13 and is approximately 29 kb in length. This allele, which encodes tyrosine-protein phosphatase… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
BACKGROUND & AIMS Recently, we reported that sorafenib sensitizes hepatocellular carcinoma (HCC) cells to TRAIL through the… (More)
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Highly Cited
2007
Highly Cited
2007
The activation of signal transducers and activators of transcription 3 (STAT3) has been linked with the proliferation of a… (More)
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Highly Cited
2003
Highly Cited
2003
Here, we present data suggesting a novel mechanism for regulation of natural killer (NK) cell cytotoxicity through inhibitory… (More)
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Highly Cited
2001
Highly Cited
2001
Mutations in hepatocyte nuclear factor 1alpha (HNF-1alpha) lead to maturity-onset diabetes of the young type 3 as a result of… (More)
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Highly Cited
1999
Highly Cited
1999
Leishmania-induced macrophage (Mphi) dysfunctions have been correlated with altered signaling events. Recent findings from our… (More)
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Highly Cited
1999
Highly Cited
1999
Biliary glycoprotein (Bgp, C-CAM, or CD66a) is an immunoglobulin-like cell adhesion molecule and functions as a tumor suppressor… (More)
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Highly Cited
1998
Highly Cited
1998
The protein tyrosine phosphatase SHP-1 is a critical regulator of macrophage biology, but its detailed mechanism of action… (More)
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Highly Cited
1998
Highly Cited
1998
The protein-tyrosine phosphatase SHP-1 binds to and dephosphorylates the epidermal growth factor receptor (EGFR), and both SH2… (More)
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Highly Cited
1998
Highly Cited
1998
Interleukin 2 (IL-2) rapidly induces tyrosine phosphorylation of intracellular substrates, including the IL-2 receptor beta chain… (More)
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Highly Cited
1996
Highly Cited
1996
Activating mutations in the Kit receptor tyrosine kinase have been identified in both rodent and human mast cell leukemia. One… (More)
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