Skip to search formSkip to main contentSkip to account menu

PTPN6 wt Allele

Known as: Protein Tyrosine Phosphatase, Non-Receptor Type 6 wt Allele, SHP-1L, HCPH 
Human PTPN6 wild-type allele is located within 12p13 and is approximately 29 kb in length. This allele, which encodes tyrosine-protein phosphatase… 
National Institutes of Health

Related topics

Related topics

15 relations
12p13ApoptosisB Cell Receptor Signaling PathwayCell Differentiation process

Broader (1)

PTPN6 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
B cell receptor signaling suppressor SHP-1 is active in CLL lymph node and peripheral blood
Protein tyrosine phosphatase SHP-1 expression and activity is downregulated or lost in several leukemias and lymphomas due to DNA… 
2015
2015
Anti-CD20 Therapy Acts via Fc g RIIIA to Diminish Responsiveness of Human Natural Killer Cells
Natural killer (NK) immune cells mediate antibody-dependent cellular cytotoxicity (ADCC) by aggregating Fc g RIIIA/CD16… 
2015
2015
MicroRNA-4649-3 p inhibits cell proliferation by targeting protein tyrosine phosphatase SHP-1 in nasopharyngeal carcinoma cells
The present study aimed to investigate the influence of microRNA-4649-3p on nasopharyngeal carcinoma (NPC) cell proliferation and… 
2012
2012
[Experimental study of SHP-1 promoter methylation in myelodysplastic syndromes and its related mechanism].
OBJECTIVE To explore the role of SHP-1 promoter methylation on the pathogenesis and progression in myelodysplastic syndromes (MDS… 
2012
2012
Cancers Depleted − Kinase / Phosphatase : Potential for Targeting SHP-1 Genetic Screening for Synthetic Lethal Partners of Polynucleotide
A genetic screen using a library of 6,961 siRNAs led to the identification of SHP-1 (PTPN6), a tumor suppressor frequently… 
2011
2011
Corrigendum: Phosphatase SHP-1 promotes TLR- and RIG-I-activated production of type I interferon by inhibiting the kinase IRAK1
Nat. Immunol. 9, 542–550 (2008); published online 6 April 2008; corrected after print 22 December 2010 In the version of this… 
2010
2010
Expressions of SHP-1 and caspase-1,and -3 in acute leukemia
Objevtive To explore the association of the expressions of hematopoietic cell phosphatase (SHP-1) gene and cysteinyl aspartate… 
1999
1999
Interconnexions entre voies de signalisation des recepteurs de cytokines et recepteurs couples aux g-proteines : shp-1, un element critique commun des signaux transductionnels du lif et de la somato…
Il est maintenant bien demontre que les recepteurs tyrosine kinase et les recepteurs couples aux g-proteines possedent en commun… 
1999
1999
SHP-1 in Apoptosis Interdependent Regulation of Intracellular Acidification and Updated Version
The G protein-coupled receptor agonist somatostatin (SST)-induces apoptosis in MCF-7 human breast cancer cells. This is… 
1998
1998
RIIb inhibits both B cell receptor-and CD 19-induced Ca 2 F mobilization in Fc γ R-transfected human B cells
FcγRIIb (CD32) controls antibody production by down-regulating cell activation, when co-clustered with B cell antigen receptors… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)