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Recent Developments in Delivery, Bioavailability, Absorption and Metabolism of Curcumin: the Golden Pigment from Golden Spice
Curcumin (diferuloylmethane) is a yellow pigment present in the spice turmeric (Curcuma longa) that has been associated with antioxidant, anti-inflammatory, anticancer, antiviral, and antibacterialExpand
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Curcumin and Cancer Cells: How Many Ways Can Curry Kill Tumor Cells Selectively?
Cancer is a hyperproliferative disorder that is usually treated by chemotherapeutic agents that are toxic not only to tumor cells but also to normal cells, so these agents produce major side effects.Expand
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Curcumin, a component of golden spice: from bedside to bench and back.
Although the history of the golden spice turmeric (Curcuma longa) goes back thousands of years, it is only within the past century that we learned about the chemistry of its active component,Expand
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Multitargeting by turmeric, the golden spice: From kitchen to clinic.
Although much has been published about curcumin, which is obtained from turmeric, comparatively little is known about turmeric itself. Turmeric, a golden spice obtained from the rhizome of the plantExpand
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Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases
Curcumin, a yellow pigment in the Indian spice Turmeric (Curcuma longa), which is chemically known as diferuloylmethane, was first isolated exactly two centuries ago in 1815 by two German Scientists,Expand
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Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals
Almost 25 centuries ago, Hippocrates, the father of medicine, proclaimed “Let food be thy medicine and medicine be thy food.” Exploring the association between diet and health continues today. ForExpand
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Multitargeting by curcumin as revealed by molecular interaction studies.
Curcumin (diferuloylmethane), the active ingredient in turmeric (Curcuma longa), is a highly pleiotropic molecule with anti-inflammatory, anti-oxidant, chemopreventive, chemosensitization, andExpand
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NF-κB and cancer: how intimate is this relationship
NF-κB, a transcription factor first discovered in 1986, is now known to be closely connected to the process of tumorogenesis based on a multiplicity of evidence. (1) NF-κB is activated in response toExpand
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Cancer drug discovery by repurposing: teaching new tricks to old dogs.
Progressively increasing failure rates, high cost, poor bioavailability, poor safety, limited efficacy, and a lengthy design and testing process associated with cancer drug development haveExpand
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Resveratrol induces apoptosis involving mitochondrial pathways in mouse skin tumorigenesis.
Resveratrol, a plant constituent enriched in the skin of grapes, is one of the most promising agents for chemoprevention. In the present study, resveratrol-induced apoptosis in 7,Expand
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