PTPN6 gene

Known as: HEMATOPOIETIC CELL PHOSPHATASE, protein tyrosine phosphatase, non-receptor type 6, PROTEIN-TYROSINE PHOSPHATASE, NONRECEPTOR-TYPE, 6 
This gene plays a role in the regulation of multiple signaling pathways in hematopoietic cells.
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
The tissue inhibitors of metalloproteinases (TIMPs) regulate matrix metalloproteinase activity required for cell migration… (More)
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Highly Cited
2000
Highly Cited
2000
The fruit, which mediates the maturation and dispersal of seeds, is a complex structure unique to flowering plants. Seed… (More)
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Highly Cited
2000
Highly Cited
2000
The SH2 domain-containing tyrosine phosphatase PTPN6 (SHP-1, PTP1C, HCP) is a 68 kDa cytoplasmic protein primarily expressed in… (More)
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Highly Cited
2000
Highly Cited
2000
CD33 is a myeloid specific member of the sialic acid-binding receptor family and is expressed highly on myeloid progenitor cells… (More)
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Highly Cited
1998
Highly Cited
1998
Subsets of T and natural killer (NK) lymphocytes express the CD94-NKG2A heterodimer, a receptor for major histocompatibility… (More)
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Highly Cited
1997
Highly Cited
1997
Two signaling molecules have been implicated in the modulation of immune receptor activation by inhibitory coreceptors: an… (More)
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Highly Cited
1997
Highly Cited
1997
The lytic activity of natural killer (NK) cells is inhibited by the expression of class I major histocompatibility complex (MHC… (More)
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Highly Cited
1996
Highly Cited
1996
Protein tyrosine phosphorylation plays a key role in regulating eukaryotic cell proliferation and differentiation. Genetic… (More)
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Highly Cited
1995
Highly Cited
1995
Coligation of the Fc receptor on B cells, Fc gamma RIIB1, with the B cell antigen receptor (BCR) leads to abortive BCR signaling… (More)
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Highly Cited
1995
Highly Cited
1995
PTPN6, a protein tyrosine phosphatase with two Src homology-2 domains, is expressed predominantly in cells of the hematopoietic… (More)
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