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PTMA protein, human
Known as:
PTMA
, Prothymosin Alpha
Prothymosin alpha (111 aa, ~12 kDa) is encoded by the human PTMA gene. This protein may play a role in the regulation of apoptosis.
National Institutes of Health
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Related topics
Related topics
7 relations
Apoptosis
Immune System Processes
PTMA gene
Recombinant Prothymosin Alpha
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Novel molecular targets regulated by tumor suppressors microRNA-1 and microRNA-133a in bladder cancer.
T. Yamasaki
,
H. Yoshino
,
+7 authors
M. Nakagawa
International Journal of Oncology
2012
Corpus ID: 5378042
Our expression signatures of human cancer including bladder cancer (BC) revealed that the expression of microRNA-1…
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Highly Cited
2005
Highly Cited
2005
Antiapoptotic function of RNA‐binding protein HuR effected through prothymosin α
A. Lal
,
T. Kawai
,
Xiaoling Yang
,
K. Mazan-Mamczarz
,
M. Gorospe
EMBO Journal
2005
Corpus ID: 38206681
We report the antiapoptotic effect of RNA‐binding protein HuR, a critical regulator of the post‐transcriptional fate of target…
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Highly Cited
2000
Highly Cited
2000
Modulation of Histone Acetyltransferase Activity through Interaction of Epstein-Barr Nuclear Antigen 3C with Prothymosin Alpha
M. Cotter
,
E. Robertson
Molecular and Cellular Biology
2000
Corpus ID: 5976343
ABSTRACT The Epstein-Barr virus (EBV) nuclear antigen 3C (EBNA3C) is essential for EBV-dependent immortalization of human primary…
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Review
2000
Review
2000
Fifteen years of prothymosin alpha: contradictory past and new horizons
A. Piñeiro
,
O. Cordero
,
M. Nogueira
Peptides
2000
Corpus ID: 24664634
Highly Cited
1999
Highly Cited
1999
Natively unfolded human prothymosin alpha adopts partially folded collapsed conformation at acidic pH.
V. Uversky
,
J. R. Gillespie
,
+9 authors
V. Abramov
Biochemistry
1999
Corpus ID: 7042423
Prothymosin alpha has previously been shown to be unfolded at neutral pH, thus belonging to a growing family of "natively…
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Highly Cited
1990
Highly Cited
1990
Thymosins: both nuclear and cytoplasmic proteins.
Julian D. Watts
,
Peter D. Cary
,
Pierre Sautiere
,
Colyn Crane-Robinson
European Journal of Biochemistry
1990
Corpus ID: 30905959
A simple procedure based on perchloric acid extraction has been developed for the preparation and purification of bovine…
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Highly Cited
1989
Highly Cited
1989
Isolation and partial sequencing of the human prothymosin alpha gene family. Evidence against export of the gene products.
W. Eschenfeldt
,
R. E. Manrow
,
M. Krug
,
S. L. Berger
Journal of Biological Chemistry
1989
Corpus ID: 2379810
Prothymosin alpha and thymosin alpha 1 are believed to be thymus-derived, hormone-like materials with immunomodulatory functions…
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Highly Cited
1986
Highly Cited
1986
The human prothymosin alpha gene is polymorphic and induced upon growth stimulation: evidence using a cloned cDNA.
W. Eschenfeldt
,
S. L. Berger
Proceedings of the National Academy of Sciences…
1986
Corpus ID: 28032273
Clones for human prothymosin alpha have been identified in cDNA libraries from staphylococcal enterotoxin A-stimulated normal…
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Highly Cited
1986
Highly Cited
1986
Molecular cloning of cDNA for human prothymosin alpha.
G. Goodall
,
F. Domı́nguez
,
B. Horecker
Proceedings of the National Academy of Sciences…
1986
Corpus ID: 7778529
A cDNA library was constructed from human spleen mRNA and screened for clones containing cDNAs coding for prothymosin alpha. A…
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Highly Cited
1984
Highly Cited
1984
Distribution of prothymosin alpha in rat tissues.
A. Haritos
,
O. Tsolas
,
B. Horecker
Proceedings of the National Academy of Sciences…
1984
Corpus ID: 38201727
A radioimmunoassay, using a rabbit antiserum directed against thymosin alpha 1, was employed to detect the presence of…
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