Skip to search formSkip to main contentSkip to account menu

Recombinant Prothymosin Alpha

Known as: Prothymosin Alpha 
A recombinant form of the endogenous polypeptide hormone that exerts immunomodulatory effects primarily on mononuclear cells. Prothymosin alpha… 
National Institutes of Health

Related topics

Related topics

3 relations
PTMA genePTMA protein, humanprothymosin alpha

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Prothymosin α variants isolated from CD8+ T cells and cervicovaginal fluid suppress HIV-1 replication through type I interferon induction.
Soluble factors from CD8(+) T cells and cervicovaginal mucosa of women are recognized as important in controlling human… 
2014
2014
Immune responses induced by the TLR-4 agonist-based adjuvant prothymosin alpha.
11131 Background: The immunomodulator prothymosin α (proTα) stimulates immune subpopulations via generating an optimized cytokine… 
2006
2006
The immunologically active site of prothymosin α is located at the carboxy-terminus of the polypeptide. Evaluation of its in vitro effects in cancer patients
Prothymosin α (proTα) is a 109 amino acid long polypeptide presenting distinct immunoenhancing activity in vitro and in vivo… 
2005
2005
Promotion of murine antitumour activity by prothymosin α treatment: I. Induction of tumoricidal peritoneal cells producing high levels of tumour necrosis factor α
SummaryThe effect of prothymosin α (ProTα) on the survival of DBA/2 mice inoculated with syngeneic tumour cells was studied. DBA… 
2002
2002
Study on the biological activity of recombinant human prothymosin α in vitro
OBJECTIVE To study on the biological activity of human prothymosin α(ProTα) in vitro.METHODS The effects of ProTα on the E… 
2001
2001
Retrovirus-mediated transfer of prothymosin gene inhibits tumor growth and prolongs survival in murine bladder cancer
To explore the potential use of prothymosin α(ProT), a putative thymic hormone, in gene therapy for bladder cancer, we generated… 
1999
1999
Increased generation of autologous tumor-reactive lymphocytes by anti-CD3 monoclonal antibody and prothymosin α
Abstract Anti-CD3 monoclonal antibody (mAb) activates in vitro peripheral blood mononuclear cells (PBMC) to lyse a variety of… 
1998
1998
Prothymosin α Stimulates Ca2+-dependent Phosphorylation of Elongation Factor 2 in Cellular Extracts*
Prothymosin α (PTA) stimulates in a dose-dependent manner the phosphorylation of a 105-kDa protein (p105) in cell extracts from… 
1997
1997
Recombinant human prothymosin alpha influences on immunity and behaviour
Highly Cited
1991
Highly Cited
1991
Expression of the rat prothymosin alpha gene during T-lymphocyte proliferation and liver regeneration.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)