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Recombinant Prothymosin Alpha
Known as:
Prothymosin Alpha
A recombinant form of the endogenous polypeptide hormone that exerts immunomodulatory effects primarily on mononuclear cells. Prothymosin alpha…
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National Institutes of Health
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Related topics
Related topics
3 relations
PTMA gene
PTMA protein, human
prothymosin alpha
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
ProT-α gene transfer attenuates cardiopulmonary remedying and mortality in a flow-induced pulmonary hypertension rat model.
J. Roan
,
Chih-Hsin Hsu
,
+4 authors
C. Lam
The Journal of heart and lung transplantation…
2020
Corpus ID: 219931378
2017
2017
57PIn vivo study of the vaccine adjuvants prothymosin alpha and prothymosin alpha(100-109) in melanoma
P. Samara
,
K. Ioannou
,
+6 authors
O. Tsitsilonis
2017
Corpus ID: 79491882
2015
2015
Prothymosin α variants isolated from CD8+ T cells and cervicovaginal fluid suppress HIV-1 replication through type I interferon induction.
A. Teixeira
,
Benjamin Yen
,
+10 authors
A. Mosoian
The Journal of infectious diseases
2015
Corpus ID: 205135744
Soluble factors from CD8(+) T cells and cervicovaginal mucosa of women are recognized as important in controlling human…
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2014
2014
Immune responses induced by the TLR-4 agonist-based adjuvant prothymosin alpha.
P. Samara
,
K. Ioannou
,
+5 authors
O. Tsitsilonis
2014
Corpus ID: 81537712
11131 Background: The immunomodulator prothymosin α (proTα) stimulates immune subpopulations via generating an optimized cytokine…
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2013
2013
Generation of Mature Nα-Terminal Acetylated Thymosin α1 by Cleavage of Recombinant Prothymosin α
Bo Liu
,
X. Gong
,
Shao-hong Chang
,
Peng Sun
,
Jun Wu
TheScientificWorldJournal
2013
Corpus ID: 27331903
Nα-terminal acetylation of peptides plays an important biological role but is rarely observed in prokaryotes. Nα-terminal…
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2005
2005
The immunologically active site of prothymosin α is located at the carboxy-terminus of the polypeptide. Evaluation of its in vitro effects in cancer patients
Margarita Skopeliti
,
I. Voutsas
,
+8 authors
O. Tsitsilonis
Cancer Immunology, Immunotherapy
2005
Corpus ID: 33964607
Prothymosin α (proTα) is a 109 amino acid long polypeptide presenting distinct immunoenhancing activity in vitro and in vivo…
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2002
2002
Study on the biological activity of recombinant human prothymosin α in vitro
Guo Bao-yu
2002
Corpus ID: 88143317
OBJECTIVE To study on the biological activity of human prothymosin α(ProTα) in vitro.METHODS The effects of ProTα on the E…
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2001
2001
Prothymosin alpha enhances protective immune responses induced by oral DNA vaccination against pseudorabies delivered by Salmonella choleraesuis.
A. Shiau
,
Y. Chen
,
C. Liao
,
Y. S. Huang
,
C. L. Wu
Vaccine
2001
Corpus ID: 35707128
1999
1999
Increased generation of autologous tumor-reactive lymphocytes by anti-CD3 monoclonal antibody and prothymosin α
C. Baxevanis
,
G. Spanakos
,
+4 authors
M. Papamichail
Cancer Immunology, Immunotherapy
1999
Corpus ID: 24954868
Abstract Anti-CD3 monoclonal antibody (mAb) activates in vitro peripheral blood mononuclear cells (PBMC) to lyse a variety of…
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1998
1998
Prothymosin α Stimulates Ca2+-dependent Phosphorylation of Elongation Factor 2 in Cellular Extracts*
F. Vega
,
A. Vidal
,
U. Hellman
,
C. Wernstedt
,
F. Domínguez
The Journal of Biological Chemistry
1998
Corpus ID: 24679030
Prothymosin α (PTA) stimulates in a dose-dependent manner the phosphorylation of a 105-kDa protein (p105) in cell extracts from…
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