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PTGIS wt Allele

Known as: MGC126858, PGIS, MGC126860 
Human PTGIS wild-type allele is located in the vicinity of 20q13.13 and is approximately 64 kb in length. This allele, which encodes prostacyclin… 
National Institutes of Health

Related topics

Related topics

8 relations
20q13.13Arachidonic Acid Metabolism PathwayOxidation-ReductionProstacyclin synthase

Broader (1)

PTGIS gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Cyclooxygenase-2 derived PGE2 and PGI2 play an important role via EP2 and PPARdelta receptors in early steps of oil induced decidualization in mice.
2008
2008
Human Follicular Dendritic Cells Interact with T Cells via Expression and Regulation of Cyclooxygenases and Prostaglandin E and I Synthases1
PGE2 inhibits mature T cell proliferation and protects T cells from activation-induced cell death (AICD). We have previously… 
Highly Cited
2007
Highly Cited
2007
COX-2 suppresses tissue factor expression via endocannabinoid-directed PPARδ activation
Although cyclooxygenase (COX)-2 inhibitors (coxibs) are effective in controlling inflammation, pain, and tumorigenesis, their use… 
2006
2006
Engineering of a protein with cyclooxygenase and prostacyclin synthase activities that converts arachidonic acid to prostacyclin.
Prostacyclin (PGI2), a vascular protector with vasodilation and antithrombotic properties, is synthesized by coupling reactions… 
2006
2006
Induction of Prostacyclin/PGI2 Synthase Expression After Cerebral Ischemia–Reperfusion
Prostacyclin (PGI2), a potent vasodilator and inhibitor of platelet aggregation and leukocyte activation, is crucial in vascular… 
2006
2006
Acceleration of wound healing by combined gene transfer of hepatocyte growth factor and prostacyclin synthase with Shima Jet
Although skin diseases are one of the target diseases for gene therapy, there has been no practical gene transfer method. First… 
Highly Cited
2004
Highly Cited
2004
Cyclooxygenase-2-derived endogenous prostacyclin enhances mouse embryo hatching.
INTRODUCTION The role of prostaglandins (PGs) in embryo hatching remains controversial. In addition, there is no direct evidence… 
Highly Cited
2003
Highly Cited
2003
Mechanosensing role of caveolae and caveolar constituents in human endothelial cells
A variety of evidence suggests that endothelial cell functions are impaired in altered gravity conditions. Nevertheless, the… 
Review
2002
Review
2002
Involvement of caveolae and caveolae-like domains in signalling, cell survival and angiogenesis.
1997
1997
Nonsense mutation of prostacyclin synthase gene in a family
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