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PTGES2 wt Allele
Known as:
Prostaglandin E Synthase 2 wt Allele
, Chromosome 9 Open Reading Frame 15 Gene
, GBF1
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Human PTGES2 wild-type allele is located in the vicinity of 9q34.11 and is approximately 8 kb in length. This allele, which encodes prostaglandin E…
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National Institutes of Health
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Related topics
Related topics
4 relations
9q34.11
Arachidonic Acid Metabolism Pathway
Prostaglandin Production
Transcriptional Regulation
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
COX-2 but Not mPGES-1 Contributes to Renal PGE2 Induction and Diabetic Proteinuria in Mice with Type-1 Diabetes
Zhanjun Jia
,
Ying Sun
,
Shanshan Liu
,
Y. Liu
,
Tianxin Yang
PLoS ONE
2014
Corpus ID: 14163050
Prostaglandin E2 (PGE2) has been implicated to play a pathogenic role in diabetic nephropathy (DN) but its source remains unlcear…
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2013
2013
PPARγ Agonist Rosiglitazone Suppresses Renal mPGES-1/PGE2 Pathway in db/db Mice
Ying Sun
,
Zhanjun Jia
,
+4 authors
Tianxin Yang
PPAR Research
2013
Corpus ID: 8025351
Evidence had shown the detrimental effect of prostaglandin (PG) E2 in diabetic nephropathy (DN) of STZ-induced type-1 diabetes…
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2013
2013
The ArfGEF GBF-1 Is Required for ER Structure, Secretion and Endocytic Transport in C. elegans
Karin B. Ackema
,
U. Sauder
,
J. Solinger
,
A. Spang
PLoS ONE
2013
Corpus ID: 4076249
Small GTPases of the Sar/Arf family are essential to generate transport containers that mediate communication between organelles…
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2012
2012
Temporal expression of the PGE2 synthetic system in the kidney is associated with the time frame of renal developmental vulnerability to cyclooxygenase-2 inhibition.
Stefanie Frölich
,
Anke Olliges
,
N. Kern
,
Yannik Schreiber
,
S. Narumiya
,
R. Nüsing
AJP - Renal Physiology
2012
Corpus ID: 6438135
Pharmacological blockade of cyclooxygenase-2 (COX-2) causes impairment of kidney development. The present study was aimed at…
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Highly Cited
2010
Highly Cited
2010
Role of MAP kinases in regulating expression of antioxidants and inflammatory mediators in mouse keratinocytes following exposure to the half mustard, 2-chloroethyl ethyl sulfide.
Adrienne T. Black
,
L. Joseph
,
+5 authors
J. Laskin
Toxicology and Applied Pharmacology
2010
Corpus ID: 24433393
Highly Cited
2009
Highly Cited
2009
Microsomal prostaglandin E synthase-2 is not essential for in vivo prostaglandin E2 biosynthesis.
Leigh A. Jania
,
Subhashini Chandrasekharan
,
+6 authors
B. Koller
Prostaglandins & other lipid mediators
2009
Corpus ID: 207434225
2007
2007
Down‐regulation of Microsomal Prostaglandin E2 Synthase‐1 in Adipose Tissue by High‐fat Feeding
P. Hétu
,
D. Riendeau
Obesity
2007
Corpus ID: 23067634
Objective: Prostaglandin (PG)E2 is a lipid mediator implicated in inflammatory diseases and in the regulation of lipolysis and…
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2007
2007
Pulmonary and Cardiorenal Cyclooxygenase-1 (COX-1), -2 (COX-2), and Microsomal Prostaglandin E Synthase-1 (mPGES-1) and -2 (mPGES-2) Expression in a Hypertension Model
Z. Radi
,
Robert A. Ostroski
Mediators of Inflammation
2007
Corpus ID: 981709
Hypertensive mice that express the human renin and angiotensinogen genes are used as a model for human hypertension because they…
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2006
2006
Expression of mouse membrane-associated prostaglandin E2 synthase-2 (mPGES-2) along the urogenital tract.
Guangrui Yang
,
Lihong Chen
,
+7 authors
Y. Guan
Biochimica et Biophysica Acta
2006
Corpus ID: 42674826
2005
2005
Roles of cyclooxygenase 2 and microsomal prostaglandin E synthase 1 in rat acid reflux oesophagitis
Tsuyoshi Hayakawa
,
Y. Fujiwara
,
+8 authors
Tetsuo Arakawa
Gut
2005
Corpus ID: 42150921
Background: Although prostaglandin E2 (PGE2), cyclooxygenase 2 (COX-2), and microsomal prostaglandin E synthase 1 (mPGES-1) are…
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